NAGK antibody (N-Acetylglucosamine Kinase) (AA 31-61)

Details for Product anti-NAGK Antibody No. ABIN391111, Supplier: Log in to see
Antigen
  • GNK
  • HSA242910
  • Gnk
  • N-acetyl-l-glutamate kinase
  • N-acetylglucosamine kinase
  • n-acetylglucosamine kinase
  • N-acetylglucosamine kinase L homeolog
  • N-acetyl-l-glutamate kinase
  • NAGK
  • Nagk
  • TTE0216
  • TVG_RS01040
  • PTO_RS00050
  • VF_2145
  • nagK
  • Bm1_35310
  • Deide_2p00250
  • APA01_RS02155
  • Ftrac_3084
  • Pedsa_2544
  • nagk.L
Epitope
AA 31-61, N-Term
22
17
17
4
3
2
2
2
2
1
1
1
1
Reactivity
Human, Mouse (Murine)
82
31
9
1
Host
Rabbit
51
28
3
Clonality (Clone)
Polyclonal ()
Conjugate
This NAGK antibody is un-conjugated
6
6
6
5
5
4
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
74
61
15
15
15
3
3
2
2
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Immunogen This NAGK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 31-61 AA from the N-terminal region of human NAGK.
Clone RB5450
Isotype Ig
Specificity This NAGK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38~68 amino acids from the N-terminal region of human NAGK.
Predicted Reactivity Cow (Bovine)
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name NAGK (NAGK Antibody Abstract)
Background N-acetylglucosamine kinase (NAGK) converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate. NAGK belongs to the group of N-acetylhexosamine kinases and is a prominent salvage enzyme of amino sugar metabolism in mammals. The predicted 344-amino acid NAGK protein contains the 5 sequence motifs necessary for the binding of ATP by sugar kinases. NAGK shares 91.6% amino acid similarity with mouse Nagk, for which enzyme activity is detectable in all mouse tissues examined, with highest enzymatic activity in testis. It is hypothesized that NAGK has a general role in the catabolic pathways of GlcNAc as well as of ManNAc.
Synonyms: N-acetylglucosamine kinase, GlcNAc kinase
Molecular Weight 37375 DA
Gene ID 55577
NCBI Accession NP_060037
Research Area Phospho-specific antibodies, Cell Signaling, Protein Modifications, Metabolism, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-N-Acetylglucosamine Kinase (NAGK) (AA 31-61), (N-Term) antibody (ABIN391111) The anti-NAGK Pab (ABIN391111) is used in Western blot to detect NAGK in mouse thymus...
Background publications Hinderlich, Berger, Schwarzkopf, Effertz, Reutter: "Molecular cloning and characterization of murine and human N-acetylglucosamine kinase." in: European journal of biochemistry / FEBS, Vol. 267, Issue 11, pp. 3301-8, 2000 (PubMed).

Lowes, Walker, Alberti, Agius: "Hexokinase isoenzymes in normal and cirrhotic human liver: suppression of glucokinase in cirrhosis." in: Biochimica et biophysica acta, Vol. 1379, Issue 1, pp. 134-42, 1998 (PubMed).

Did you look for something else?