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AMHR2 antibody (Anti-Mullerian Hormone Receptor, Type II) (AA 13-42)

Details for Product anti-AMHR2 Antibody No. ABIN391173, Supplier: Log in to see
Antigen
  • AMHR
  • MISR2
  • MISRII
  • MRII
  • Misiir
  • Misrii
  • Mrii
  • anti-Mullerian hormone receptor, type II
  • anti-Mullerian hormone type 2 receptor
  • AMHR2
  • Amhr2
Epitope
AA 13-42, N-Term
20
15
5
3
3
3
2
2
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
70
30
20
1
1
1
1
1
Host
Rabbit
60
4
4
2
Clonality (Clone)
Polyclonal ()
Conjugate
This AMHR2 antibody is un-conjugated
4
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
50
28
13
7
7
6
3
3
2
1
Options
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Immunogen This AMHR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-42 AA from the N-terminal region of human AMHR2.
Clone RB8486
Isotype Ig
Specificity This AMHR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20~50 amino acids from the N-terminal region of human AMHR2.
Predicted Reactivity Rabbit
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name AMHR2 (AMHR2 Antibody Abstract)
Background The AMH receptor (AMHR or AMHR2) is a serine/threonine kinase with a single transmembrane domain belonging to the family of type II receptors for TGF-beta-related proteins. Anti-Mullerian hormone (AMH) and its receptor are involved in the regression of Mullerian ducts in male fetuses. Male sex differentiation is mediated by 2 discrete hormones produced by the fetal testis. Testosterone, produced by Leydig cells, virilizes the external genitalia and promotes prostatic growth, anti-Mullerian hormone (AMH) results in regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes.
Synonyms: Anti-Muellerian hormone type II receptor [Precursor], AMH type II receptor, MIS type II receptor, MISRII, MRII, AMHR2, AMHR,
Molecular Weight 62750 DA
Gene ID 269
UniProt Q16671
Research Area Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-AMHR2 antibody (Anti-Mullerian Hormone Receptor, Type II) (AA 13-42) (ABIN391173) Western blot analysis of AMHR2 Antibody (N-term) (ABIN391173) in mouse testis tissue ...
Product cited in: Almeida, Conley, Ball: "Expression of anti-Müllerian hormone, CDKN1B, connexin 43, androgen receptor and steroidogenic enzymes in the equine cryptorchid testis." in: Equine veterinary journal, Vol. 45, Issue 5, pp. 538-45, 2013 (PubMed).

Almeida, Conley, Mathewson, Ball: "Expression of anti-Müllerian hormone, cyclin-dependent kinase inhibitor (CDKN1B), androgen receptor, and connexin 43 in equine testes during puberty." in: Theriogenology, Vol. 77, Issue 5, pp. 847-57, 2012 (PubMed).

Almeida, Ball, Conley, Place, Liu, Scholtz, Mathewson, Stanley, Moeller: "Biological and clinical significance of anti-Müllerian hormone determination in blood serum of the mare." in: Theriogenology, Vol. 76, Issue 8, pp. 1393-403, 2011 (PubMed).

Background publications Visser, McLuskey, van Beers, Weghuis, van Kessel, Grootegoed, Themmen: "Structure and chromosomal localization of the human anti-müllerian hormone type II receptor gene." in: Biochemical and biophysical research communications, Vol. 215, Issue 3, pp. 1029-36, 1995 (PubMed).