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ERN2 antibody (N-Term)

ERN2 Reactivity: Human WB Host: Rabbit Polyclonal RB8519 unconjugated
Catalog No. ABIN391194
  • Target See all ERN2 Antibodies
    ERN2 (Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2))
    Binding Specificity
    • 17
    • 9
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 39-72, N-Term
    Reactivity
    • 28
    • 19
    Human
    Host
    • 43
    • 1
    Rabbit
    Clonality
    • 44
    Polyclonal
    Conjugate
    • 17
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ERN2 antibody is un-conjugated
    Application
    • 31
    • 31
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This ERN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-72 amino acids from the N-terminal region of human ERN2.
    Clone
    RB8519
    Isotype
    Ig Fraction
    Top Product
    Discover our top product ERN2 Primary Antibody
  • Application Notes
    WB: 1:1000. WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    ERN2 (Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2))
    Alternative Name
    ERN2 (ERN2 Products)
    Synonyms
    Ire1beta antibody, ire1b antibody, Ern1 antibody, Ire1 antibody, Ire1b antibody, IRE1-BETA antibody, IRE1b antibody, endoplasmic reticulum to nucleus signaling 2 antibody, endoplasmic reticulum (ER) to nucleus signalling 2 antibody, ERN2 antibody, ern2 antibody, Ern2 antibody
    Background
    ERN2 induces translational repression through 28S ribosomal RNA cleavage in response to endoplasmic reticulum (ER) stress. This pro-apoptotic appears to play no role in the unfolded-protein response, unlike closely related proteins. Overexpression of ERN2 activates both BiP and CHOP expression, and also leads to the development of programmed cell death. It has been suggested that Ern2 plays a role in multiple facets of the ER stress response in mammalian cells.
    Molecular Weight
    102480
    Gene ID
    10595
    NCBI Accession
    NP_150296
    UniProt
    Q76MJ5
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