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LMTK2 antibody (Lemur tyrosine Kinase 2) (AA 70-100)

Details for Product anti-LMTK2 Antibody No. ABIN391208, Supplier: Log in to see
Antigen
  • 2900041G10Rik
  • A330101P12Rik
  • AATYK2
  • aatyk2
  • BREK
  • cprk
  • KPI-2
  • KPI2
  • LMR2
Alternatives
anti-Human LMTK2 antibody for Enzyme Immunoassay
Epitope
AA 70-100, N-Term
19
18
8
3
3
1
1
1
1
1
1
Reactivity
Human
67
3
2
2
1
1
1
Host
Rabbit
43
14
10
Clonality (Clone)
Polyclonal ()
Conjugate
This LMTK2 antibody is un-conjugated
3
3
3
3
3
3
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
59
49
31
12
10
6
2
Supplier
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Immunogen This LMTK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-100 AA from the N-terminal region of human LMTK2.
Clone RB8233
Isotype Ig
Specificity This LMTK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 78~107 amino acids from the N-terminal region of human LMTK2.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name LMTK2 (LMTK2 Antibody Abstract)
Background Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).
Synonyms: KPI-2 protein, LMTK2,
Molecular Weight 164927 DA
Gene ID 22853
UniProt Q8IWU2
Research Area Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Cycle, Transcription Factors, Signaling, Metabolism, Cell Structure
Pathways RTK Signaling, Neurotrophin Signaling Pathway
Application Notes WB = 1:1000, IHC (p) = 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-LMTK2 antibody (Lemur tyrosine Kinase 2) (AA 70-100) (ABIN391208) Western blot analysis of LTK2 N-term (ABIN391208) in Hela cell line lysates (35 µg/la...
Immunohistochemistry (IHC) image for anti-LMTK2 antibody (Lemur tyrosine Kinase 2) (AA 70-100) (ABIN391208) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary ant...
Background publications Scherer, Cheung, MacDonald, Osborne, Nakabayashi, Herbrick, Carson, Parker-Katiraee, Skaug, Khaja, Zhang, Hudek, Li, Haddad, Duggan, Fernandez, Kanematsu, Gentles, Christopoulos, Choufani, Kwasnicka et al.: "Human chromosome 7: DNA sequence and biology. ..." in: Science (New York, N.Y.), Vol. 300, Issue 5620, pp. 767-72, 2003 (PubMed).

Kesavapany, Lau, Ackerley, Banner, Shemilt, Cooper, Leigh, Shaw, McLoughlin, Miller: "Identification of a novel, membrane-associated neuronal kinase, cyclin-dependent kinase 5/p35-regulated kinase." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 23, Issue 12, pp. 4975-83, 2003 (PubMed).

Wang, Brautigan: "A novel transmembrane Ser/Thr kinase complexes with protein phosphatase-1 and inhibitor-2." in: The Journal of biological chemistry, Vol. 277, Issue 51, pp. 49605-12, 2002 (PubMed).