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Details for Product No. ABIN391223

Maternal Embryonic Leucine Zipper Kinase (MELK) (AA 201-230), (Center) antibody

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Antigen
Synonyms HPK38, MPK38, AI327312, mKIAA0175, fb71b01, fe01f04, wu:fb71b01, wu:fe01f04, xmelk, MELK, Melk
Epitope
»Alternatives AA 201-230, Center
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN391223
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This MELK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 201-230 AA from the Central region of human MELK.
Clone RB8556
Isotype Ig
Specificity This MELK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 208~238 amino acids from the center region of human MELK.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name MELK
Background MELK contains 1 protein kinase domain that belongs to the Ser/Thr protein kinase family. It phosphorylates ZNF622 and may contribute to its redirection to the nucleus. MELK may also be involved in the inhibition of spliceosome assembly during mitosis.
Synonyms: Maternal embryonic leucine zipper kinase, hMELK, Protein kinase PK38, hPK38, MELK, KIAA0175,
Molecular Weight 74642 DA
Gene ID 9833
UniProt Q14680
Research Area Phospho-specific antibodies, Stem Cells, Cell Signaling, Protein Modifications, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Davezac, Baldin, Blot et al.: "Human pEg3 kinase associates with and phosphorylates CDC25B phosphatase: a potential role for pEg3 in cell cycle regulation." in: Oncogene, Vol. 21, Issue 50, pp. 7630-41, 2002 (PubMed).

Alternatives for antigen "Maternal Embryonic Leucine Zipper Kinase (MELK)", type "Antibodies"
Hosts (39), (11), (5)
Reactivities (54), (19), (16), (15), (15), (12), (1), (1)
Applications (40), (26), (10), (5), (5), (4), (3), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (13), (3), (2), (2), (2), (2), (1), (1), (1), (1)
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