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Maternal Embryonic Leucine Zipper Kinase (MELK) (AA 201-230), (Center) antibody

Details for Product No. ABIN391223, Supplier: Log in to see
Antigen
  • MELK
  • xmelk
  • Melk
  • HPK38
  • AI327312
  • MPK38
  • mKIAA0175
  • fb71b01
  • fe01f04
  • wu:fb71b01
  • wu:fe01f04
Epitope
AA 201-230, Center
41
18
13
12
3
3
3
2
2
2
2
2
2
1
1
1
1
1
Reactivity
Human
109
27
18
6
6
2
2
2
2
2
Host
Rabbit
86
20
8
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
6
6
6
5
5
5
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
85
60
11
8
7
5
5
5
3
2
1
Supplier
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Immunogen This MELK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 201-230 AA from the Central region of human MELK.
Clone RB8556
Isotype Ig
Specificity This MELK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 208~238 amino acids from the center region of human MELK.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name MELK (MELK Antibody Abstract)
Background MELK contains 1 protein kinase domain that belongs to the Ser/Thr protein kinase family. It phosphorylates ZNF622 and may contribute to its redirection to the nucleus. MELK may also be involved in the inhibition of spliceosome assembly during mitosis.
Synonyms: Maternal embryonic leucine zipper kinase, hMELK, Protein kinase PK38, hPK38, MELK, KIAA0175,
Molecular Weight 74642 DA
Gene ID 9833
UniProt Q14680
Research Area Phospho-specific antibodies, Stem Cells, Cell Signaling, Protein Modifications, Cell Structure
Pathways
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Maternal Embryonic Leucine Zipper Kinase (MELK) (AA 201-230), (Center) antibody (ABIN391223) The anti-MRLK Pab (ABIN391223) is used in Western blot to detect MRLK in mouse brain ...
Background publications Davezac, Baldin, Blot et al.: "Human pEg3 kinase associates with and phosphorylates CDC25B phosphatase: a potential role for pEg3 in cell cycle regulation." in: Oncogene, Vol. 21, Issue 50, pp. 7630-41, 2002 (PubMed).