Pantothenate Kinase 1 (PANK1) (N-Term), (AA 75-105) antibody

Details for Product No. ABIN391235
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Antigen
Epitope
N-Term, AA 75-105
(8), (7), (2), (2), (2), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(42), (15), (15), (12), (12), (12)
Host
Rabbit
(40), (2)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(30), (19), (10), (9), (7), (2), (2), (2), (2), (1)
Pubmed 1 reference available
Quantity 400 μL
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Catalog No. ABIN391235
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Immunogen This PANK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-105 AA from the N-terminal region of human PANK1.
Clone RB5481
Isotype Ig
Specificity This PANK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 83~112 amino acids from the N-terminal region of human PANK1.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name PANK1
Background PANK1 belongs to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA.
Synonyms: Pantothenate kinase 1, Pantothenic acid kinase 1, hPanK1, hPanK, PANK1, PANK,
Molecular Weight 64339 DA
Gene ID 53354
UniProt Q8TE04
Research Area Phospho-specific antibodies, Cell Signaling, Protein Modifications, Metabolism, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Pantothenate Kinase 1 (PANK1) (N-Term), (AA 75-105) antibody Western blot analysis of hPANK1-R90 (ABIN391235) in MCF-7 cell line and mouse spleen tissue lysates (35 µg/lane). PANK1 (arrow) was detected using the purified polyclonal antibody.
Background publications Zhou, Westaway, Levinson et al.: "A novel pantothenate kinase gene (PANK2) is defective in Hallervorden-Spatz syndrome." in: Nature genetics, Vol. 28, Issue 4, pp. 345-9, 2001 (PubMed).

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