PIKFYVE antibody (AA 1531-1561)

Catalog No. ABIN391254

Product Details anti-PIKFYVE Antibody

Target: PIKFYVE (phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE))

Binding Specificity: AA 1531-1561

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIKFYVE antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This PIP5K3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1531-1561 amino acids from the Central region of human PIP5K3.

Clone: RB5311

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-PIKFYVE antibody (ABIN391254)

Alesutan, Ureche, Laufer, Klaus, Zürn, Lindner, Strutz-Seebohm, Tavaré, Boehmer, Palmada, Lang, Seebohm, Lang: "Regulation of the glutamate transporter EAAT4 by PIKfyve." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 25, Issue 2-3, pp. 187-94, (2010) (PubMed).

Target Details for PIKFYVE

Target: PIKFYVE (phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE))

Alternative Name: PIP5K3 (PIKFYVE Products)

Background: PIP5K3 belongs to a large family of lipid kinases that alter the phosphorylation status of intracellular phosphatidylinositol. Signaling by phosphorylated species of phosphatidylinositol regulates diverse cellular processes, including membrane trafficking and cytoskeletal reorganization.

Molecular Weight: 237136

Gene ID: 200576

NCBI Accession: NP_001171471, NP_055855, NP_689884

UniProt: Q9Y2I7

Pathways: Inositol Metabolic Process