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PRKAA1 antibody (Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit) (AA 479-510)

Details for Product anti-PRKAA1 Antibody No. ABIN391303, Supplier: Log in to see
Antigen
  • Prkaa1
  • ampk
  • ampka1
  • PRKAA1
  • AMPK
  • AMPKa1
  • AMPKalpha1
  • AI194361
  • AI450832
  • AL024255
  • C130083N04Rik
  • cb116
  • im:7154392
  • sb:cb130
  • wu:fa94c10
  • AMPK1
Alternatives
anti-Human PRKAA1 antibody for Immunoprecipitation
Epitope
AA 479-510, C-Term
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Reactivity
Human, Mouse (Murine)
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Host
Rabbit
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Clonality (Clone)
Polyclonal ()
Conjugate
This PRKAA1 antibody is un-conjugated
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Application
Western Blotting (WB)
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10
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Supplier
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Immunogen This AMPK alpha 1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 479-510 AA from the C-terminal region of human AMPK alpha 1.
Clone RB2520
Isotype Ig
Specificity This AMPK alpha 1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 487~517 amino acids from the C-terminal region of human AMPK alpha 1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name AMPK alpha 1 (PRKAA1 Antibody Abstract)
Background AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. It appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. AMPK alpha1, a member of the Ser/Thr protein kinase family, is a catalytic subunit of AMPK.
Synonyms: 5'-AMP-activated protein kinase, catalytic alpha-1 chain, AMPK alpha-1 chain
Molecular Weight 62793 DA
Gene ID 5562
UniProt Q13131
Research Area Apoptosis/Necrosis, Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Structure
Pathways AMPK Signaling
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-PRKAA1 antibody (Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit) (AA 479-510) (ABIN391303) Western blot analysis of anti-AMPK alpha 1 C-term Pab (ABIN391303) in mouse liver lys...
Western Blotting (WB) image for anti-PRKAA1 antibody (Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit) (AA 479-510) (ABIN391303) AMPKalpha1 Antibody (C494) (ABIN391303) western blot analysis in SK-BR-3 cell line ly...
Background publications Zhang, Ye, Wu et al.: "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells." in: Genome research, Vol. 10, Issue 10, pp. 1546-60, 2000 (PubMed).