Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) (C-Term), (AA 446-478) antibody

Details for Product No. ABIN391311
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Antigen
Synonyms CAMKA, PKCCD, PK2CDD, zgc:112538, zgc:123320, camk2, camk2b
Epitope
C-Term, AA 446-478
(20), (9), (5), (5), (5), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(70), (52), (38), (9), (6), (6), (6), (5), (5), (5), (3), (2), (2), (1), (1), (1), (1)
Host
Rabbit
(64), (31), (6)
Clonality (Clone)
Polyclonal ()
Application
Western Blotting (WB), Immunohistochemistry (IHC)
(96), (40), (30), (22), (11), (10), (8), (7), (4), (4), (3), (2), (2), (2)
Pubmed 1 reference available
Catalog no. ABIN391311
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This CAMK2A (CAMK2 alpha) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 446-478 AA from the C-terminal region of human CAMK2A (CAMK2 alpha).
Clone RB1258
Isotype Ig
Specificity This CAMK2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human CAMK2.
Predicted Reactivity Mouse (Murine),Rat (Rattus)
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name CAMK2A (CAMK2 alpha)
Background CaM-kinase II (CAMK2) is a prominent Ser/Thr protein kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Likely autophosphorylation of Thr-286 allows the kinase to switch from a calmodulin-dependent to a calmodulin-independent state. CAMK2 is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits.
Synonyms: Calcium/calmodulin-dependent protein kinase type II alpha chain, CaM-kinase II alpha chain, CaM kinase II alpha subunit, CaMK-II alpha subunit
Molecular Weight 54029 DA
Gene ID 815
UniProt Q9UQM7
Research Area Phospho-specific antibodies, Cell Signaling, Protein Modifications, Neurology, Cell Structure
Application Notes WB = 1:1000, IHC = 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 1.64 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) (C-Term), (AA 446-478) antibody Western blot analysis of anti-CAMK2 alpha C-term Pab (ABIN391311) in 293 cell lysate. CAMK2 alpha (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
anti-Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) (C-Term), (AA 446-478) antibody (2) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma
anti-Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) (C-Term), (AA 446-478) antibody (3) Formalin-fixed and paraffin-embedded human brain tissue reacted with CAMK2 alpha Antibody (C-term) (ABIN391311), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
Background publications Blume-Jensen, Hunter: "Oncogenic kinase signalling." in: Nature, Vol. 411, Issue 6835, pp. 355-65, 2001 (PubMed).

Hosts (64), (31), (6)
Reactivities (70), (52), (38), (9), (6), (6), (6), (5), (5), (5), (3), (2), (2), (1), (1), (1), (1)
Applications (96), (40), (30), (22), (11), (10), (8), (7), (4), (4), (3), (2), (2), (2)
Epitopes (20), (9), (5), (5), (5), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
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