Mitogen-Activated Protein Kinase 14 (MAPK14) (AA 301-330), (Tyr323) antibody

Details for Product No. ABIN391332
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Antigen
Synonyms
P38C-CRK, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA, CRK1, Csbp1, Csbp2, Exip, Hog, Prkm14, Prkm15, Sapk2A, p38Hog, p38alpha, Crk1, p38-alpha, p38MAPK, p38a, csb ... show more
P38C-CRK, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA, CRK1, Csbp1, Csbp2, Exip, Hog, Prkm14, Prkm15, Sapk2A, p38Hog, p38alpha, Crk1, p38-alpha, p38MAPK, p38a, csbp, mapk14a, mxi2, sapk2, sapk2a, p38b, zp38b, MAPK14, 186F5S, BG:DS00797.3, CG7393, D-p38, D-p38 MAPK, D-p38b, Dm p38b, Dmel\\CG7393, Dmp38b, Dp38, Dp38b, ESTS:186F5S, Mpk34C, anon-sts23, dp38b, p38 MAPK, p38 beta, p38B, p38Kb, p38beta show less
Epitope
AA 301-330, Tyr323
(89), (74), (18), (16), (16), (13), (13), (9), (6), (6), (6), (5), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(312), (218), (215), (77), (48), (41), (15), (10), (6), (6), (5), (5), (5), (2), (1), (1), (1)
Host
Rabbit
(287), (37), (2), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(7), (6), (5), (5), (5), (5), (5), (5), (5), (5), (5)
Application
Western Blotting (WB), Flow Cytometry (FACS)
(257), (113), (86), (53), (50), (45), (23), (19), (9), (8), (8), (3), (3), (2), (2), (1), (1), (1), (1)
Pubmed 2 references available
Catalog no. ABIN391332
Quantity 400 µL
Price
238.50 $   Plus shipping costs $45.00
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  • +1 404 474 4654
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Immunogen This MAPK14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 301-330 AA from human MAPK14.
Clone RB13245
Isotype Ig
Specificity This MAPK14 (p38) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding Y323 of human MAPK14.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name MAPK14 (p38)
Background MAPK14 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response.
Synonyms: Mitogen-activated protein kinase 14, Mitogen-activated protein kinase p38alpha, MAP kinase p38alpha, Cytokine suppressive anti-inflammatory drug binding protein, CSAID binding protein, CSBP, MAX-interacting protein 2, MAP kinase MXI2, SAPK2A
Molecular Weight 41293 DA
Gene ID 1432
UniProt Q16539
Research Area Protein Modifications, Cancer, Cell Cycle, Transcription Factors, Signaling, Cell Structure
Application Notes WB = 1:1000, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.28 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (AA 301-330), (Tyr323) antibody Western blot analysis of MAPK14 Antibody (Y322) (ABIN391332) in HepG2 cell line lysates (35 µg/lane). MAPK14(arrow) was detected using the purified polyclonal antibody (1:60 dilution).
anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (AA 301-330), (Tyr323) antibody (2) Western blot analysis of MAPK14(arrow) using rabbit polyclonal MAPK14 Antibody (Y322) (ABIN391332). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the MAPK14 gene (Lane 2) (Origene Technologies).
Background publications Dean, Sarsfield, Tsounakou et al.: "p38 Mitogen-activated protein kinase stabilizes mRNAs that contain cyclooxygenase-2 and tumor necrosis factor AU-rich elements by inhibiting deadenylation." in: The Journal of biological chemistry, Vol. 278, Issue 41, pp. 39470-6, 2003 (PubMed).

Cheung, Campbell, Nebreda et al.: "Feedback control of the protein kinase TAK1 by SAPK2a/p38alpha." in: The EMBO journal, Vol. 22, Issue 21, pp. 5793-805, 2003 (PubMed).

Hosts (287), (37), (2), (1)
Reactivities (312), (218), (215), (77), (48), (41), (15), (10), (6), (6), (5), (5), (5), (2), (1), (1), (1)
Applications (257), (113), (86), (53), (50), (45), (23), (19), (9), (8), (8), (3), (3), (2), (2), (1), (1), (1), (1)
Conjugates (7), (6), (5), (5), (5), (5), (5), (5), (5), (5), (5)
Epitopes (89), (74), (18), (16), (16), (13), (13), (9), (6), (6), (6), (5), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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