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Amyloid beta Precursor Protein (Cytoplasmic Tail) Binding Protein 2 (APPBP2) (AA 242-271), (Center) antibody

Details for Product No. ABIN391423, Supplier: Log in to see
Antigen
  • zgc:76971
  • wu:fb78e11
  • wu:fc25c09
  • APPBP2
  • DKFZp459F0530
  • HS.84084
  • PAT1
  • 1300003O07Rik
  • AI465480
  • Dct1
  • LYAAT1
  • TRAMD3
Epitope
AA 242-271, Center
25
21
17
16
4
3
2
2
2
2
2
2
1
Reactivity
Human
97
32
30
3
1
1
1
1
1
Host
Rabbit
93
6
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
7
7
7
6
6
6
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
67
62
24
11
6
3
3
1
1
Supplier
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Immunogen This PAT1(APPBP2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 242-271 AA from the Central region of human PAT1(APPBP2).
Clone RB8985
Isotype Ig
Specificity This PAT1(APPBP2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 249~279 amino acids from the Center region of human PAT1.
Predicted Reactivity Mouse (Murine),Rat (Rattus)
Purification This antibody is purified through a protein G column, followed by dialysis against PBS.
Alternative Name PAT1 (APPBP2) (APPBP2 Antibody Abstract)
Background APPBP2 interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. This protein has been found to be highly expressed in breast cancer.
Synonyms: Amyloid protein-binding protein 2, Amyloid beta precursor protein-binding protein 2, APP-BP2, Protein interacting with APP tail 1, APPBP2, KIAA0228, PAT1
Molecular Weight 66722 DA
Gene ID 10513
NCBI Accession NP_006371
Research Area Cell Signaling, Cell Structure, Neurology
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 1.85 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Amyloid beta Precursor Protein (Cytoplasmic Tail) Binding Protein 2 (APPBP2) (AA 242-271), (Center) antibody (ABIN391423) Western blot analysis of anti-PAT1 (APPBP2) Antibody (Center) (ABIN391423) in HL60 ce...
Background publications Zheng, Eastman, Vande Pol et al.: "PAT1, a microtubule-interacting protein, recognizes the basolateral sorting signal of amyloid precursor protein." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 25, pp. 14745-50, 1999 (PubMed).