Mitogen-Activated Protein Kinase 4 (MAPK4) (C-Term), (AA 537-566) antibody

Details for Product No. ABIN391466
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Antigen
Synonyms ERK-4, ERK3, Erk4, MAPK 4, PRKM4, p63MAPK, A330097D03Rik, Erk3, Prkm4, p63Mapk, erk4, wu:fi27d11, zgc:55498, ATMPK4, F2N1.1, F2N1_1, MAP kinase 4
Epitope
C-Term, AA 537-566
(20), (11), (7), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(43), (21), (13), (1), (1), (1), (1)
Host
Rabbit
(43), (5), (2), (1), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(39), (20), (16), (12), (10), (6), (4), (1), (1)
Pubmed 3 references available
Quantity 400 µL
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Catalog No. ABIN391466
291.50 $
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Immunogen This MAPK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 537-566 AA from the C-terminal region of human MAPK4.
Clone RB14448
Isotype Ig
Specificity This MAPK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 544~574 amino acids from the C-term of human MAPK4.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name MAPK4
Background Mitogen-activated protein kinase 4 is a member of the mitogen-activated protein kinase family. Tyrosine kinase growth factor receptors activate mitogen-activated protein kinases which then translocate into the nucleus where it phosphorylates nuclear targets.
Synonyms: Mitogen-activated protein kinase 4, Mitogen-activated protein kinase 4, isoform CRA_a, MAPK4
Molecular Weight 65922 DA
Gene ID 5596
UniProt Q0VG04
Research Area Cell Cycle, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Mitogen-Activated Protein Kinase 4 (MAPK4) (C-Term), (AA 537-566) antibody Western blot analysis of anti-MAPK4 Antibody (C-term) (ABIN391466) in Jurkat cell line lysates (35 µg/lane). MAPK4(arrow) was detected using the purified polyclonal antibody (1:60 dilution).
Background publications Seger, Krebs: "The MAPK signaling cascade." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 9, Issue 9, pp. 726-35, 1995 (PubMed).

Kant, Schumacher, Singh et al.: "Characterization of the atypical MAPK ERK4 and its activation of the MAPK-activated protein kinase MK5." in: The Journal of biological chemistry, Vol. 281, Issue 46, pp. 35511-9, 2006 (PubMed).

Lerner-Marmarosh, Miralem, Gibbs et al.: "Human biliverdin reductase is an ERK activator; hBVR is an ERK nuclear transporter and is required for MAPK signaling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 19, pp. 6870-5, 2008 (PubMed).

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