ADAM Metallopeptidase with thrombospondin Type 1 Motif, 5 (ADAMTS5) (AA 331-360), (Center) antibody

Details for Product No. ABIN391652
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Antigen
Synonyms 9530092O11Rik, ADAM-TS5, ADAMTS1, ADAMTS11, AI481094, ASMP-2, ADAM-TS 11, ADAM-TS 5, ADAMTS-11, ADAMTS-5, ADMP-2
Epitope
AA 331-360, Center
(14), (14), (11), (7), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Mouse (Murine)
(71), (19), (16), (13), (13), (12)
Host
Rabbit
(70), (1), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(45), (23), (22), (10), (5), (4), (2), (2), (1), (1), (1), (1)
Pubmed 2 references available
Quantity 400 μL
Options
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Catalog No. ABIN391652
291.50 $
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Immunogen This ADAMTS5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 331-360 AA from the Central region of human ADAMTS5.
Clone RB18038
Isotype Ig
Specificity This ADAMTS5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 338~368 amino acids from the center region of human ADAMTS5.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name ADAMTS5
Background ADAMTS5 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains.
Synonyms: A disintegrin and metalloproteinase with thrombospondin motifs 5, Aggrecanase-2, ADMP-2, A disintegrin and metalloproteinase with thrombospondin motifs 11, ADAMTS11, ADMP2
Molecular Weight 101716 DA
Gene ID 11096
UniProt Q9UNA0
Research Area Metabolism, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.49 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-ADAM Metallopeptidase with thrombospondin Type 1 Motif, 5 (ADAMTS5) (AA 331-360), (Center) antibody Western blot analysis of anti-ADAMTS5 Antibody (Center) (ABIN391652) in mouse muscle tissue lysates (35 µg/lane). ADAMTS5(arrow) was detected using the purified polyclonal antibody.
Background publications Hurskainen, Hirohata, Seldin et al.: "ADAM-TS5, ADAM-TS6, and ADAM-TS7, novel members of a new family of zinc metalloproteases. General features and genomic distribution of the ADAM-TS family." in: The Journal of biological chemistry, Vol. 274, Issue 36, pp. 25555-63, 1999 (PubMed).

Tortorella, Pratta, Liu et al.: "The thrombospondin motif of aggrecanase-1 (ADAMTS-4) is critical for aggrecan substrate recognition and cleavage." in: The Journal of biological chemistry, Vol. 275, Issue 33, pp. 25791-7, 2000 (PubMed).

Validation Images
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