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ADAM Metallopeptidase with thrombospondin Type 1 Motif, 5 (ADAMTS5) (AA 331-360), (Center) antibody

Details for Product No. ABIN391652, Supplier: Login to see
Antigen
  • 9530092O11Rik
  • ADAM-TS5
  • ADAMTS1
  • ADAMTS11
  • AI481094
  • ASMP-2
  • ADAM-TS 11
  • ADAM-TS 5
  • ADAMTS-11
  • ADAMTS-5
  • ADMP-2
Epitope
AA 331-360, Center
27
22
15
14
13
10
8
3
3
2
2
2
1
1
1
1
Reactivity
Mouse (Murine)
107
25
21
1
1
Host
Rabbit
106
2
2
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
5
5
5
4
4
4
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
62
46
33
16
11
4
4
2
2
1
Supplier
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Immunogen This ADAMTS5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 331-360 AA from the Central region of human ADAMTS5.
Clone RB18038
Isotype Ig
Specificity This ADAMTS5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 338~368 amino acids from the center region of human ADAMTS5.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name ADAMTS5 (ADAMTS5 Antibody Abstract)
Background ADAMTS5 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains.
Synonyms: A disintegrin and metalloproteinase with thrombospondin motifs 5, Aggrecanase-2, ADMP-2, A disintegrin and metalloproteinase with thrombospondin motifs 11, ADAMTS11, ADMP2
Molecular Weight 101716 DA
Gene ID 11096
UniProt Q9UNA0
Research Area Metabolism, Cell Structure
Pathways
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.49 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-ADAM Metallopeptidase with thrombospondin Type 1 Motif, 5 (ADAMTS5) (AA 331-360), (Center) antibody (ABIN391652) Western blot analysis of anti-ADAMTS5 Antibody (Center) (ABIN391652) in mouse muscle ...
Background publications Tortorella, Pratta, Liu et al.: "The thrombospondin motif of aggrecanase-1 (ADAMTS-4) is critical for aggrecan substrate recognition and cleavage." in: The Journal of biological chemistry, Vol. 275, Issue 33, pp. 25791-7, 2000 (PubMed).

Hurskainen, Hirohata, Seldin et al.: "ADAM-TS5, ADAM-TS6, and ADAM-TS7, novel members of a new family of zinc metalloproteases. General features and genomic distribution of the ADAM-TS family." in: The Journal of biological chemistry, Vol. 274, Issue 36, pp. 25555-63, 1999 (PubMed).