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CDK18 antibody (N-Term)

CDK18 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB3364 unconjugated
Catalog No. ABIN391790
  • Target See all CDK18 Antibodies
    CDK18 (Cyclin-Dependent Kinase 18 (CDK18))
    Binding Specificity
    • 8
    • 8
    • 8
    • 7
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 25-55, N-Term
    Reactivity
    • 40
    • 33
    • 10
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 57
    • 2
    Rabbit
    Clonality
    • 59
    Polyclonal
    Conjugate
    • 20
    • 7
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This CDK18 antibody is un-conjugated
    Application
    • 45
    • 33
    • 14
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This PCTAIRE3 (PCTK3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-55 amino acids from the N-terminal region of human PCTAIRE3 (PCTK3).
    Clone
    RB3364
    Isotype
    Ig Fraction
  • Application Notes
    WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    CDK18 (Cyclin-Dependent Kinase 18 (CDK18))
    Alternative Name
    PCTAIRE3 (PCTK3) (CDK18 Products)
    Synonyms
    PCTK3 antibody, DKFZp468H0312 antibody, PCTAIRE antibody, PCTAIRE3 antibody, AA682070 antibody, Ctk18 antibody, Pctk3 antibody, cyclin dependent kinase 18 antibody, cyclin-dependent kinase 18 antibody, CDK18 antibody, Cdk18 antibody
    Background
    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway. The CMGC group consists of 60 kinases including the cyclin-dependent kinase (CDK) and close relatives family, the MAP kinase (ERK) family, the glycogen synthase kinase 3 (GSK3) family, and the Cdc2-like kinase (CLK) family.
    Molecular Weight
    54424
    Gene ID
    5129
    NCBI Accession
    NP_002587, NP_997667, NP_997668
    UniProt
    Q07002
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