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EARS2 antibody (C-Term)
EARS2
Reactivity: Human
WB, IHC (p)
Host: Rabbit
Polyclonal
RB14808
unconjugated
Product Details anti-EARS2 Antibody
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Target
See all EARS2 Antibodies
EARS2
(Glutamyl-tRNA Synthetase 2 Mitochondrial (EARS2))
Binding Specificity
All epitopes for EARS2 antibodies
AA 495-523, C-Term
Reactivity
All reactivities for EARS2 antibodies
Human
Host
All hosts for EARS2 antibodies
Rabbit
Clonality
All clonalities for EARS2 antibodies
Polyclonal
Conjugate
All conjugates for EARS2 antibodies
This EARS2 antibody is un-conjugated
Application
All applications for EARS2 antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This EARS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 495-523 amino acids from the C-terminal region of human EARS2.
Clone
RB14808
Isotype
Ig Fraction
Alternatives
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Application Details
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Application Notes
WB: 1:1000. IHC-P: 1:10~50
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
References for anti-EARS2 antibody (ABIN391828)
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Boczonadi, Smith, Pyle, Gomez-Duran, Schara, Tulinius, Chinnery, Horvath : "Altered 2-thiouridylation impairs mitochondrial translation in reversible infantile respiratory chain deficiency. " in: Human molecular genetics , Vol. 22 , Issue 22 , pp. 4602-15 , (2013 ) (PubMed ).
Target Details for EARS2
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Target
EARS2
(Glutamyl-tRNA Synthetase 2 Mitochondrial (EARS2))
Alternative Name
EARS2 (EARS2 Products )
Synonyms
mse1 antibody, 3230401I01Rik antibody, AL024049 antibody, mKIAA1970 antibody, COXPD12 antibody, MSE1 antibody, RGD1307904 antibody, ears2 antibody, glutamyl-tRNA synthetase 2, mitochondrial antibody, zgc:153247 antibody, EARS2 antibody, ears2 antibody, Ears2 antibody, zgc:153247 antibody
Background
Glutamyl-tRNA synthetase (GluRS or EARS2) a class I aminoacyl-tRNA synthetase (aaRS), is primarily responsible for the glutamylation of tRNAGlu. It is part of the ?minimal set?of seventeen aaRSs found in every living organism and its presence is essential for the viability of cells.
Molecular Weight
58689
Gene ID
124454
NCBI Accession
NP_001077083
UniProt
Q5JPH6
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