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Ret Proto-Oncogene antibody (C-Term)

RET Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB01561 unconjugated
Catalog No. ABIN392041
  • Target See all Ret Proto-Oncogene (RET) Antibodies
    Ret Proto-Oncogene (RET)
    Binding Specificity
    • 27
    • 21
    • 20
    • 16
    • 15
    • 15
    • 15
    • 14
    • 8
    • 8
    • 8
    • 8
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1012-1042, C-Term
    Reactivity
    • 182
    • 100
    • 81
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 205
    • 22
    • 2
    • 1
    • 1
    • 1
    Rabbit
    Clonality
    • 200
    • 32
    Polyclonal
    Conjugate
    • 89
    • 18
    • 14
    • 13
    • 10
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 1
    This Ret Proto-Oncogene antibody is un-conjugated
    Application
    • 190
    • 102
    • 66
    • 65
    • 58
    • 27
    • 22
    • 16
    • 15
    • 10
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This RET antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1012-1042 amino acids from the C-terminal region of human RET.
    Clone
    RB01561
    Isotype
    Ig Fraction
    Top Product
    Discover our top product RET Primary Antibody
  • Application Notes
    WB: 1:1000. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • de Martimprey, Bertrand, Fusco, Santoro, Couvreur, Vauthier, Malvy: "siRNA nanoformulation against the ret/PTC1 junction oncogene is efficient in an in vivo model of papillary thyroid carcinoma." in: Nucleic acids research, Vol. 36, Issue 1, pp. e2, (2008) (PubMed).

  • Target
    Ret Proto-Oncogene (RET)
    Alternative Name
    RET (RET Products)
    Synonyms
    c-ret antibody, cret antibody, etID315074.13 antibody, ret1 antibody, wu:fd13h01 antibody, X-ret antibody, ret-A antibody, xret antibody, RET antibody, MTC1 antibody, CDHF12 antibody, CDHR16 antibody, HSCR1 antibody, MEN2A antibody, MEN2B antibody, PTC antibody, RET-ELE1 antibody, RET51 antibody, RET9 antibody, c-Ret antibody, ret proto-oncogene receptor tyrosine kinase antibody, ret proto-oncogene S homeolog antibody, ret proto-oncogene antibody, ret antibody, ret.S antibody, RET antibody, Ret antibody
    Background
    RET, a member of the cadherin superfamily, is one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This protein plays a crucial role in neural crest development, and the gene can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations i are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma.
    Molecular Weight
    124319
    Gene ID
    5979
    NCBI Accession
    NP_065681, NP_066124
    UniProt
    P07949
    Pathways
    RTK Signaling, Dopaminergic Neurogenesis, Regulation of Cell Size, Tube Formation
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