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ANTXR1 antibody (AA 358-386)
ANTXR1
Reactivity: Human
WB, IHC (p)
Host: Rabbit
Polyclonal
RB15324
unconjugated
Product Details anti-ANTXR1 Antibody
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Target
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ANTXR1
(anthrax Toxin Receptor 1 (ANTXR1))
Binding Specificity
All epitopes for ANTXR1 antibodies
AA 358-386
Reactivity
All reactivities for ANTXR1 antibodies
Human
Host
All hosts for ANTXR1 antibodies
Rabbit
Clonality
All clonalities for ANTXR1 antibodies
Polyclonal
Conjugate
All conjugates for ANTXR1 antibodies
This ANTXR1 antibody is un-conjugated
Application
All applications for ANTXR1 antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Predicted Reactivity
M, Rat
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This ANTXR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 358-386 amino acids from human ANTXR1.
Clone
RB15324
Isotype
Ig Fraction
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Discover our top product ANTXR1 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB: 1:1000. IHC-P: 1:10~50
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
Target Details for ANTXR1
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Target
ANTXR1
(anthrax Toxin Receptor 1 (ANTXR1))
Alternative Name
ANTXR1 (ANTXR1 Products )
Synonyms
ANTXR1 antibody, ATR antibody, TEM8 antibody, 2310008J16Rik antibody, 2810405N18Rik antibody, Antrx1 antibody, Tem8 antibody, anthrax toxin receptor 1 antibody, ANTXR1 antibody, Antxr1 antibody
Background
ANTXR1 is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. This protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes.
Molecular Weight
62789
Gene ID
84168
NCBI Accession
NP_060623 , NP_115584 , NP_444262
UniProt
Q9H6X2
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