Activin A Receptor, Type IIB (ACVR2B) (Center R147) antibody

Antigen: Activin A Receptor, Type IIB (ACVR2B)

Synonyms: FOP, ALK2, SKR1, TSRI, ACTRI, ACVR1A, ACVRLK2, ACTRIIB, ActR-IIB, MGC116908, ActRIIB, MGC118477, actr2b, actrIIb, wu:fj97d11, ACVR2B, Acvr2b, actriib, MGC89569, actr-iib

Epitope: Center R147

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN392240

Additional Information

Characteristics: Purified Rabbit Polyclonal Antibody (Pab)

Alternative name: Activin Receptor Type IA (ACVR1) (Center R147)

Gene ID: 90

Swiss-Prot: Q04771

Immunogen: This ACVR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140~169 amino acids from the center region of human ACVR1.

Isotype: Ig  (Matching secondary antibodies)

Description: Other names: Activin receptor type I, ACTR-I, Serine/threonine-protein kinase receptor R1, SKR1, Activin receptor-like kinase 2, ALK-2, TGF-B superfamily receptor type I, TSR-I, ACVRLK2

Specificity: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human ACVR1.

Molecular Weight: 57153 DA

Application Details

Application Notes: The suggested dilution is: ELISA~~1:1,000 Western blotting~~1:100~500 Immunohistochemistry~~1:50~100

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.Preca

Research Area: Phospho-specific antibodies, Protein Modifications, Cell Structure, Cell Cycle, Transcription Factors, Signaling

Restrictions: For Research Use only

Images

The anti-ACVR1 Pab (ABIN392240) is used in Western blot to detect ACVR1 in HeLa cell lysate (Lane 1) and mouse liver tissue lysate (Lane 2).

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. clinical relevance has not been evaluated. BC = breast carcinoma. HC = hepatocarcinoma.

Western blot analysis of ACVR1 (arrow) using rabbit polyclonal ACVR1 Antibody (R147) (ABIN392240). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the ACVR1 gene.