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Details for Product No. ABIN392241

Activin A Receptor Type II-Like 1 (ACVRL1) (N-Term), (AA 38-68) antibody

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Antigen
Synonyms HHT, ALK1, HHT2, ORW2, SKR3, ALK-1, TSR-I, ACVRLK1, R-3, R3, SETHKIR, AI115505, AI427544, Acvrlk1, Alk1, ACVRL1, vgb, alk1, zehn1109, hm:zehn1109
Epitope
»Alternatives N-Term, AA 38-68
Reactivity
»Alternatives Human, Mouse (Murine)
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC)
Pubmed 2 references available
Catalog no. ABIN392241
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This ACVRL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-68 AA from the N-terminal region of human ACVRL1.
Clone RB03736
Isotype Ig
Specificity This ACVRL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46~76 amino acids from the N-terminal region of human ACVRL1.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name ACVRL1
Background ACVRL1 is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. This protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.
Synonyms: SKR3, Activin receptor-like kinase 1, ALK-1, TGF-B superfamily receptor type I, TSR-I
Molecular Weight 56124 DA
Gene ID 94
UniProt P37023
Research Area Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,FC : 1:10-50,IHC : 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Attisano, Cárcamo, Ventura et al.: "Identification of human activin and TGF beta type I receptors that form heteromeric kinase complexes with type II receptors." in: Cell, Vol. 75, Issue 4, pp. 671-80, 1993 (PubMed).

Strausberg, Feingold, Grouse et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, 2002 (PubMed).

Alternatives for antigen "Activin A Receptor Type II-Like 1 (ACVRL1)", type "Antibodies"
Hosts (50), (11), (8), (1)
Reactivities (66), (31), (24), (18), (17)
Applications (49), (29), (20), (19), (10), (8), (7), (3), (3), (2), (2)
Conjugates (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (8), (7), (5), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1)
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