Activin A Receptor Type II-Like 1 (ACVRL1) (N-Term) antibody

Antigen: Activin A Receptor Type II-Like 1 (ACVRL1)

Synonyms: FOP, ALK2, SKR1, TSRI, ACTRI, ACVR1A, ACVRLK2, HHT, ALK1, HHT2, ORW2, SKR3, ALK-1, TSR-I, ACVRLK1, R3, R-3, SETHKIR, MGC91691, ACVRL1, MGC139457, DKFZp459C148, vgb, alk1, zehn1109, hm:zehn1109

Epitope: N-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN392241

Additional Information

Characteristics: Purified Rabbit Polyclonal Antibody (Pab)

Alternative name: ACVRL1 (N-term)

Gene ID: 94

Swiss-Prot: P37023

Immunogen: This ACVRL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46~76 amino acids from the N-terminal region of human ACVRL1.

Isotype: Ig  (Matching secondary antibodies)

Description: Other names: SKR3, Activin receptor-like kinase 1, ALK-1, TGF-B superfamily receptor type I, TSR-I

Specificity: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human ACVRL1.

Molecular Weight: 56124 DA

Application Details

Application Notes: The suggested dilution is: ELISA~~1:1,000 Western blotting~~1:100~500 Flow cytometric~~1:10~50 Immunohistochemistry~~1:50~100

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Structure

Restrictions: For Research Use only

Images

Western blot of ACVRL1 Pab (ABIN392241). TOP LEFT: Mouse heart tissue lysate.

Western blot analysis of ACVRL1 (arrow) using rabbit polyclonal ACVRL1 Antibody (N-term) (ABIN392241). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ACVRL1 gene (Lane 2) (Origene Technologies).

human chondrocytes (C28/I2 cells), transfected with empty vector (lane 1, 3) or ACVRL1(lane 2, 4). RIPA lysis buffer, 20 ug/lane of protein, primary antibody dilution 1:1000, blocking solution is 5% milk in TBST (lane 1 and 2), 5% BSA in TBST (lane 3 and 4). Data courtesy of Kenneth Finnson, Montreal General Hospital.