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ACVRL1 antibody (C-Term)

ACVRL1 Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB03737 unconjugated
Catalog No. ABIN392242
  • Target See all ACVRL1 Antibodies
    ACVRL1 (Activin A Receptor Type II-Like 1 (ACVRL1))
    Binding Specificity
    • 13
    • 11
    • 10
    • 7
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 474-503, C-Term
    Reactivity
    • 70
    • 29
    • 17
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 64
    • 5
    • 1
    • 1
    Rabbit
    Clonality
    • 62
    • 8
    Polyclonal
    Conjugate
    • 40
    • 6
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ACVRL1 antibody is un-conjugated
    Application
    • 60
    • 41
    • 39
    • 15
    • 11
    • 10
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This ACVRL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 474-503 amino acids from the C-terminal region of human ACVRL1.
    Clone
    RB03737
    Isotype
    Ig Fraction
    Top Product
    Discover our top product ACVRL1 Primary Antibody
  • Application Notes
    WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    ACVRL1 (Activin A Receptor Type II-Like 1 (ACVRL1))
    Alternative Name
    ACVRL1 (ACVRL1 Products)
    Synonyms
    ACVRL1 antibody, vgb antibody, alk1 antibody, zehn1109 antibody, hm:zehn1109 antibody, ACVRLK1 antibody, ALK-1 antibody, ALK1 antibody, HHT antibody, HHT2 antibody, ORW2 antibody, SKR3 antibody, TSR-I antibody, R-3 antibody, R3 antibody, SETHKIR antibody, AI115505 antibody, AI427544 antibody, Acvrlk1 antibody, Alk1 antibody, activin A receptor like type 1 antibody, activin A receptor type II-like 1 antibody, activin A receptor, type II-like 1 antibody, ACVRL1 antibody, acvrl1 antibody, Acvrl1 antibody
    Background
    ACVRL1 is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. This protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.
    Molecular Weight
    56124
    Gene ID
    94
    NCBI Accession
    NP_000011, NP_001070869
    UniProt
    P37023
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