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Details for Product No. ABIN392257

Kinase Suppressor of Ras 1 (KSR1) (N-Term), (AA 1-30) antibody

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Antigen
Synonyms KSR, RSU2, hb, Ksr, B-KSR1, AW492498, D11Bhm183e, D11Bhm184e, CG2899, Dmel\\CG2899, EK3-1, KSR-1, Ksr-1, SR3-1, dKsr, l(3)j5E2
Epitope
»Alternatives N-Term, AA 1-30
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 1 reference available
Catalog no. ABIN392257
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This KSR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 AA from the N-terminal region of human KSR1.
Clone RB3309
Isotype Ig
Specificity This KSR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region with alanine at position 7 of human KSR1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name KSR1
Background Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.
Synonyms: Kinase suppressor of ras-1
Molecular Weight 71671 DA
Gene ID 8844
Research Area Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Structure, Cell Cycle, Transcription Factors, Signaling, Metabolism
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 0.42 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Blume-Jensen, Hunter: "Oncogenic kinase signalling." in: Nature, Vol. 411, Issue 6835, pp. 355-65, 2001 (PubMed).

Alternatives for antigen "Kinase Suppressor of Ras 1 (KSR1)", type "Antibodies"
Hosts (53), (4), (4)
Reactivities (57), (40), (27), (12), (12), (12), (12)
Applications (42), (23), (20), (15), (12), (7), (4), (2), (2), (1)
Conjugates (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (17), (12), (7), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
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