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Transglutaminase 2 antibody (AA 413-442)
TGM2
Reactivity: Human
WB
Host: Rabbit
Polyclonal
RB13079
unconjugated
Product Details anti-Transglutaminase 2 Antibody
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Target
See all Transglutaminase 2 (TGM2) Antibodies
Transglutaminase 2 (TGM2)
(Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))
Binding Specificity
All epitopes for Transglutaminase 2 antibodies
AA 413-442
Reactivity
All reactivities for Transglutaminase 2 antibodies
Human
Host
All hosts for Transglutaminase 2 antibodies
Rabbit
Clonality
All clonalities for Transglutaminase 2 antibodies
Polyclonal
Conjugate
All conjugates for Transglutaminase 2 antibodies
This Transglutaminase 2 antibody is un-conjugated
Application
All applications for Transglutaminase 2 antibodies
Western Blotting (WB)
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This Transglutaminase (TGM2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 413-442 amino acids from the Central region of human Transglutaminase (TGM2).
Clone
RB13079
Isotype
Ig Fraction
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Alternatives
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Application Details
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Application Notes
WB: 1:1000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
Target Details for Transglutaminase 2
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Target
Transglutaminase 2 (TGM2)
(Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))
Alternative Name
Transglutaminase (TGM2) (TGM2 Products )
Synonyms
G-ALPHA-h antibody, GNAH antibody, TG2 antibody, TGC antibody, tgm2 antibody, zgc:101081 antibody, TgaseII antibody, TGM2 antibody, fc12b04 antibody, wu:fc12b04 antibody, zgc:136700 antibody, TGL2 antibody, G[a]h antibody, TGase2 antibody, tTG antibody, tTGas antibody, transglutaminase 2 antibody, transglutaminase 2, C polypeptide A antibody, transglutaminase 2b antibody, transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) antibody, transglutaminase 2, C polypeptide antibody, TGM2 antibody, tgm2a antibody, Tgm2 antibody, tgm2b antibody
Background
Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. TGM2 acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. It has been identified as the autoantigen implicated in celiac disease.
Molecular Weight
77329
Gene ID
7052
NCBI Accession
NP_004604 , NP_945189
UniProt
P21980
Pathways
Tube Formation , Thromboxane A2 Receptor Signaling
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