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CYP2R1 antibody (AA 152-180)

CYP2R1 Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB15785 unconjugated
Catalog No. ABIN392380
  • Target See all CYP2R1 Antibodies
    CYP2R1 (Cytochrome P450, Family 2, Subfamily R, Polypeptide 1 (CYP2R1))
    Binding Specificity
    • 15
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 152-180
    Reactivity
    • 35
    • 25
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Mouse
    Host
    • 34
    • 2
    • 1
    Rabbit
    Clonality
    • 37
    Polyclonal
    Conjugate
    • 23
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CYP2R1 antibody is un-conjugated
    Application
    • 36
    • 13
    • 13
    • 10
    • 9
    • 6
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This CYP2R1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 152-180 amino acids from the Central region of human CYP2R1.
    Clone
    RB15785
    Isotype
    Ig Fraction
    Top Product
    Discover our top product CYP2R1 Primary Antibody
  • Application Notes
    WB: 1:1000. IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Ochiai, Hirose, Kawamura, Komachi, Yamamoto, Kitaoka, Hatogai, Kusunoki, Kon, Ikarashi, Sugiyama: "Role of the Drug-Metabolizing Enzyme CYP during Mouse Liver Development." in: Biological & pharmaceutical bulletin, Vol. 39, Issue 12, pp. 2015-2021, (2017) (PubMed).

  • Target
    CYP2R1 (Cytochrome P450, Family 2, Subfamily R, Polypeptide 1 (CYP2R1))
    Alternative Name
    CYP2R1 (CYP2R1 Products)
    Synonyms
    cytochrome P450 family 2 subfamily R member 1 antibody, cytochrome P450, family 2, subfamily R, polypeptide 1 antibody, cytochrome P450, family 2, subfamily r, polypeptide 1 antibody, CYP2R1 antibody, cyp2r1 antibody, Cyp2r1 antibody
    Background
    CYP2R1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in CYP2R1 gene has been associated with selective 25-hydroxyvitamin D deficiency.
    Molecular Weight
    57359
    Gene ID
    120227
    NCBI Accession
    NP_078790
    UniProt
    Q6VVX0
    Pathways
    Metabolism of Steroid Hormones and Vitamin D
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