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Aurora A antibody (Aurora Kinase A) (AA 90-120)

Details for Product anti-AURKA Antibody No. ABIN392389, Supplier: Log in to see
Antigen
  • 87A7-9/2
  • Aur-A
  • AurA
  • CG3068
  • Dmel\\CG3068
  • aur-A
  • aurA
  • ck10
  • ck[10]
  • l(3)87Ac
  • l(3)ck10
  • Aurora-A
  • Eg2
  • aik
  • ark1
  • aur-a
  • aura
  • aurora2
  • btak
  • pEg2
  • stk15
  • stk6
  • stk7
  • wu:fb37c10
  • wu:fc02c02
  • zgc:100912
  • AURKA
  • aurka
  • AIK
  • ARK1
  • AURA
  • AURORA2
  • BTAK
  • PPP1R47
  • STK15
  • STK6
  • STK7
  • AIRK1
  • AU019385
  • AW539821
  • Ark1
  • Ayk1
  • IAK
  • IAK1
  • Stk6
  • ARK-1
  • aurka-a
Alternatives
anti-Human Aurora A antibody for Immunofluorescence
Epitope
AA 90-120, N-Term
45
41
30
15
5
4
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
217
75
49
14
8
8
3
2
1
1
1
1
Host
Rabbit
168
56
19
Clonality (Clone)
Polyclonal ()
Conjugate
This Aurora A antibody is un-conjugated
12
6
6
5
5
5
2
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
185
86
77
50
33
28
15
15
12
5
4
2
1
1
Supplier
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Immunogen This AIK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-120 AA from the N-terminal region of human AIK.
Clone RB00883
Isotype Ig
Specificity This AIK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human AIK.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name AIK (AURKA Antibody Abstract)
Background Aurora A (AIK) plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.
Synonyms: Aurora/IPL1-related kinase 1, STK6, Aurora-A
Molecular Weight 46000 DA
Gene ID 6790
Research Area Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Cycle, Transcription Factors, Signaling, Metabolism, Cell Structure
Pathways Cell Division Cycle
Application Notes WB = 1:1000, IHC (p) = 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Aurora A antibody (Aurora Kinase A) (AA 90-120) (ABIN392389) Western blot analysis of AIK (arrow) using rabbit polyclonal hAIK-H105 (ABIN392389). ...
Immunohistochemistry (IHC) image for anti-Aurora A antibody (Aurora Kinase A) (AA 90-120) (ABIN392389) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary ant...
Immunohistochemistry (IHC) image for anti-Aurora A antibody (Aurora Kinase A) (AA 90-120) (ABIN392389) Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with AIK an...
Background publications Kimura, Kotani, Hattori et al.: "Cell cycle-dependent expression and spindle pole localization of a novel human protein kinase, Aik, related to Aurora of Drosophila and yeast Ipl1." in: The Journal of biological chemistry, Vol. 272, Issue 21, pp. 13766-71, 1997 (PubMed).