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PAK6 antibody (AA 116-146)

PAK6 Reactivity: Human WB Host: Rabbit Polyclonal RB1237 unconjugated
Catalog No. ABIN392439
  • Target See all PAK6 Antibodies
    PAK6 (P21-Activated Kinase 6 (PAK6))
    Binding Specificity
    • 15
    • 15
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 116-146
    Reactivity
    • 69
    • 45
    • 10
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 84
    Rabbit
    Clonality
    • 83
    Polyclonal
    Conjugate
    • 40
    • 6
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This PAK6 antibody is un-conjugated
    Application
    • 62
    • 38
    • 26
    • 26
    • 19
    • 16
    • 15
    • 12
    • 6
    • 4
    • 3
    Western Blotting (WB)
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This PAK6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-146 amino acids from human PAK6.
    Clone
    RB1237
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PAK6 Primary Antibody
  • Application Notes
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    PAK6 (P21-Activated Kinase 6 (PAK6))
    Alternative Name
    PAK6 (PAK6 Products)
    Synonyms
    PAK5 antibody, 4732456M09 antibody, pak6 antibody, si:ch211-158b22.3 antibody, p21 (RAC1) activated kinase 6 antibody, p21 protein (Cdc42/Rac)-activated kinase 6 antibody, p21 protein (Cdc42/Rac)-activated kinase 6b antibody, PAK6 antibody, Pak6 antibody, pak6b antibody
    Background
    The PAK6 protein shares a high degree of sequence similarity with p21-activated kinase (PAK) family members. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. PAK6 was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development. The p21-activated protein kinase 6 gene was found to be highly expressed in testis and prostate tissues and the encoded protein was shown to cotranslocate into the nucleus with AR in response to androgen.
    Molecular Weight
    74869
    Gene ID
    56924
    NCBI Accession
    NP_001122100, NP_001122101, NP_001263646, NP_001263647, NP_064553
    UniProt
    Q9NQU5
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