PRKX antibody (C-Term)

Catalog No. ABIN392449

Product Details anti-PRKX Antibody

Target: PRKX (Protein Kinase, X-Linked (PRKX))

Binding Specificity: AA 312-343, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRKX antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This PRKX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 312-343 amino acids from the C-terminal region of human PRKX.

Clone: RB01029

Isotype: Ig Fraction

Application Details

Application Notes: IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-PRKX antibody (ABIN392449)

Li, Iomini, Hyink, Wilson: "PRKX critically regulates endothelial cell proliferation, migration, and vascular-like structure formation." in: Developmental biology, Vol. 356, Issue 2, pp. 475-85, (2011) (PubMed).

Target Details for PRKX

Target: PRKX (Protein Kinase, X-Linked (PRKX))

Alternative Name: PRKX (PRKX Products)

Background: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group consists of 63 kinases including the cyclic nucleotide-regulated protein kinase (PKA & PKG) family, the diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family, the related to PKA and PKC (RAC/Akt) protein kinase family, the kinases that phosphorylate G protein-coupled receptors family (ARK), and the kinases that phosphorylate ribosomal protein S6 family (RSK). The calcium/calmodulin-dependent kinase (CAMK) group consists of 75 kinases regulated by Ca2+/CaM and close relative family (CAMK, CAMKL, DAPK, MAPKAPK).

Molecular Weight: 40896

Gene ID: 5613

NCBI Accession: NP_005035

UniProt: P51817

Pathways: Thyroid Hormone Synthesis