Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

MAP4K3 antibody (C-Term)

MAP4K3 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB1264 unconjugated
Catalog No. ABIN392541
  • Target See all MAP4K3 Antibodies
    MAP4K3 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 3 (MAP4K3))
    Binding Specificity
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    AA 423-453, C-Term
    Reactivity
    • 64
    • 30
    • 16
    Human
    Host
    • 62
    • 2
    Rabbit
    Clonality
    • 62
    • 2
    Polyclonal
    Conjugate
    • 24
    • 7
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This MAP4K3 antibody is un-conjugated
    Application
    • 47
    • 38
    • 37
    • 20
    • 6
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This GLK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 423-453 amino acids from the C-terminal region of human GLK.
    Clone
    RB1264
    Isotype
    Ig Fraction
    Top Product
    Discover our top product MAP4K3 Primary Antibody
  • Application Notes
    WB: 1:1000. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    MAP4K3 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 3 (MAP4K3))
    Alternative Name
    GLK (MAP4K3 Products)
    Synonyms
    GLK antibody, MAPKKKK3 antibody, MEKKK 3 antibody, MEKKK3 antibody, RAB8IPL1 antibody, 4833416M01Rik antibody, 4833416M07Rik antibody, 9530052P13Rik antibody, Glk antibody, mitogen-activated protein kinase kinase kinase kinase 3 antibody, MAP4K3 antibody, Map4k3 antibody
    Background
    GLK is a member of the Ste20 family of serine/threonine protein kinases. The protein belongs to the subfamily that consists of members, such as germinal center kinase (GCK), that are characterized by an N-terminal catalytic domain and C-terminal regulatory domain. The kinase activity of the encoded protein can be stimulated by UV radiation and tumor necrosis factor-alpha. The protein specifically activates the c-Jun N-terminal kinase (JNK) signaling pathway. Evidence suggests that it functions upstream of mitogen-activated protein kinase kinase kinase 1 (MEKK1). This gene previously was referred to as RAB8-interacting protein-like 1 (RAB8IPL1), but it has been renamed mitogen-activated protein kinase kinase kinase kinase 3 (MAP4K3).
    Molecular Weight
    101316
    Gene ID
    8491
    NCBI Accession
    NP_001257354, NP_003609
    UniProt
    Q8IVH8
    Pathways
    MAPK Signaling
You are here:
Support