PIP5K1B antibody (N-Term)

Catalog No. ABIN392594

Product Details anti-PIP5K1B Antibody

Target: PIP5K1B (Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, beta (PIP5K1B))

Binding Specificity: AA 1-30, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIP5K1B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This PIP5K1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PIP5K1B.

Clone: RB1729

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-PIP5K1B antibody (ABIN392594)

Qin, Li, Pan, Wu: "Regulation of phosphatidylinositol kinases and metabolism by Wnt3a and Dvl." in: The Journal of biological chemistry, Vol. 284, Issue 34, pp. 22544-8, (2009) (PubMed).

Bolomini-Vittori, Montresor, Giagulli, Staunton, Rossi, Martinello, Constantin, Laudanna: "Regulation of conformer-specific activation of the integrin LFA-1 by a chemokine-triggered Rho signaling module." in: Nature immunology, Vol. 10, Issue 2, pp. 185-94, (2009) (PubMed).

Target Details for PIP5K1B

Target: PIP5K1B (Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, beta (PIP5K1B))

Alternative Name: PIP5K1B (PIP5K1B Products)

Synonyms: MSS4 antibody, STM7 antibody, AI844522 antibody, Pip5k1a antibody, Pipk5a antibody, Pipk5b antibody, MGC80809 antibody, pip5k1b antibody, zgc:101046 antibody, wu:fj29b05 antibody, wu:fj93b05 antibody, zgc:92316 antibody, phosphatidylinositol-4-phosphate 5-kinase type 1 beta antibody, phosphatidylinositol-4-phosphate 5-kinase, type 1 beta antibody, phosphatidylinositol-4-phosphate 5-kinase, type I, beta L homeolog antibody, phosphatidylinositol-4-phosphate 5-kinase, type I, beta a antibody, phosphatidylinositol-4-phosphate 5-kinase, type I, beta antibody, phosphatidylinositol 4-phosphate 5-kinase type-1 beta antibody, phosphatidylinositol-4-phosphate 5-kinase, type I, beta b antibody, PIP5K1B antibody, Pip5k1b antibody, pip5k1b.L antibody, pip5k1ba antibody, pip5k1b antibody, LOC100472550 antibody, pip5k1bb antibody

Background: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.

Molecular Weight: 61036

Gene ID: 8395

NCBI Accession: NP_003549

UniProt: O14986

Pathways: PI3K-Akt Signaling, Inositol Metabolic Process, Cell-Cell Junction Organization