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tyrosine 3-Monooxygenase/tryptophan 5-Monooxygenase Activation Protein, zeta Polypeptide (YWHAZ) (AA 211-239), (Thr232) antibody

Details for Product No. ABIN392783, Supplier: Log in to see
Antigen
  • 14-3-3
  • 14-3-3 zeta
  • 14-3-3-zeta
  • 14-3-3ZETA
  • 14-3-3leo
  • 2G1
  • 4-3-3 zeta
  • 5.11
  • 549
  • BEST:GH05075
  • CG17870
  • D14-3-3
  • D14-3-3zeta
  • Dmel\\CG17870
  • K
  • LEO
  • Leo
  • PAR-5
  • PAR5
  • Par-5
  • d14-3-3zeta
  • l(2)07103
  • l(2)46CFe
  • l(2)46Ee
  • leo
  • par-5
  • 14-3-3z
  • 14-3-3zeta
  • kcip-1
  • ywhaq
  • ACYPI003154
  • 1433z
  • Ywhaz
  • 14-3-3-zetaisoform
  • Pkcz
  • r14-3-3
  • 1300003C17Rik
  • KCIP-1
  • YWHAD
  • 1110013I11Rik
  • AI596267
  • AL022924
  • AU020854
  • ywhaz
  • ywhaza
  • fb14h09
  • wu:fb05g08
  • wu:fb14h09
  • ywhai
  • zgc:55807
  • ywhazb
Alternatives
anti-Human tyrosine 3-Monooxygenase/tryptophan 5-Monooxygenase Activation Protein, zeta Polypeptide antibody for Immunocytochemistry
Epitope
AA 211-239, Thr232
46
17
12
7
6
5
5
5
4
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
171
91
82
15
14
13
11
5
3
2
2
1
1
Host
Rabbit
164
10
1
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
2
2
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
138
73
50
45
39
11
11
11
3
3
3
Supplier
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Immunogen This YWHAZ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 211-239 AA from human YWHAZ.
Clone RB7161
Isotype Ig
Specificity This 14-3-3 protein zeta/delta antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding T232 of human 14-3-3.
Predicted Reactivity Cow (Bovine),Chicken,Mouse (Murine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name 14-3-3 protein zeta/delta (YWHAZ Antibody Abstract)
Background 14-3-3 protein zeta/delta belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs.
Synonyms: 14-3-3 protein zeta/delta, Protein kinase C inhibitor protein 1, KCIP-1, YWHAZ
Molecular Weight 27745 DA
Gene ID 7534
UniProt P63104
Research Area Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Structure
Pathways Apoptosis
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-tyrosine 3-Monooxygenase/tryptophan 5-Monooxygenase Activation Protein, zeta Polypeptide (YWHAZ) (AA 211-239), (Thr232) antibody (ABIN392783) Western blot analysis of anti-14-3-3 protein zeta/delta Anbtibody (T232)(ABIN392783) ...
Immunohistochemistry (IHC) image for anti-tyrosine 3-Monooxygenase/tryptophan 5-Monooxygenase Activation Protein, zeta Polypeptide (YWHAZ) (AA 211-239), (Thr232) antibody (ABIN392783) Formalin-fixed and paraffin-embedded human testis tissue reacted with PLD1 antibody (...
Background publications Li, Mofunanya, Harris et al.: "Chibby cooperates with 14-3-3 to regulate beta-catenin subcellular distribution and signaling activity." in: The Journal of cell biology, Vol. 181, Issue 7, pp. 1141-54, 2008 (PubMed).

Li, Zhao, Du et al.: "Down-regulation of 14-3-3zeta suppresses anchorage-independent growth of lung cancer cells through anoikis activation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 1, pp. 162-7, 2008 (PubMed).