PTP4A1 antibody

Catalog No. ABIN392856

Product Details anti-PTP4A1 Antibody

Target: PTP4A1 (Protein Tyrosine Phosphatase Type IVA, Member 1 (PTP4A1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTP4A1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This PRL1 antibody is generated from rabbits immunized with a recombinant protein encoding full length of human PRL1.

Clone: RB7268

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for PTP4A1

Target: PTP4A1 (Protein Tyrosine Phosphatase Type IVA, Member 1 (PTP4A1))

Alternative Name: PRL1 (PTP4A1 Products)

Synonyms: ptp4a1 antibody, MGC83351 antibody, hh72 antibody, prl1 antibody, prl-1 antibody, MGC79517 antibody, ptpcaax1 antibody, ptp(caax1) antibody, fb54d08 antibody, fc01c04 antibody, wu:fb54d08 antibody, wu:fc01c04 antibody, zgc:101726 antibody, Ptp4a1 antibody, PRL-1 antibody, PTP4A1 antibody, PRL1 antibody, DKFZp459E022 antibody, AA415290 antibody, AU019864 antibody, C130021B01 antibody, Prl-1 antibody, HH72 antibody, PTP(CAAX1) antibody, PTPCAAX1 antibody, protein tyrosine phosphatase type IVA, member 1 antibody, protein tyrosine phosphatase type IVA, member 1 L homeolog antibody, protein tyrosine phosphatase 4a1 antibody, PTP4A1 antibody, ptp4a1.L antibody, ptp4a1 antibody, Ptp4a1 antibody

Background: The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain and a characteristic C-terminal prenylation motif. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This tyrosine phosphatase is a nuclear protein, but may primarily associate with plasma membrane. The surface membrane association of this protein depends on its C-terminal prenylation. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which implicated its role in the tumorigenesis. Studies in rat suggested that this gene may be an immediate-early gene in mitogen-stimulated cells.PRL phosphatases increase cell proliferation by stimulating progression from G1 into S phase. PRL-1 function is regulated in a cell cycle-dependent manner and implicate PRL-1 in regulating progression through mitosis, possibly by modulating spindle dynamics.

Molecular Weight: 19815

Gene ID: 7803

NCBI Accession: NP_003454

UniProt: Q93096