You are viewing an incomplete version of our website. Please click to reload the website as full version.

GAS2 antibody (Growth Arrest-Specific 2) (AA 1-111)

Details for Product anti-GAS2 Antibody No. ABIN393205, Supplier: Log in to see
Antigen
  • GAS2
  • gas2
  • si:packt119.1
  • GAS-2
  • Gas-2
  • RGD1563167
Alternatives
anti-Human GAS2 antibody for Immunofluorescence
Epitope
AA 1-111
17
17
5
4
3
2
2
1
Reactivity
Human
62
25
24
Host
Mouse
55
7
Clonality (Clone)
Monoclonal ()
Conjugate
This GAS2 antibody is un-conjugated
4
4
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (IF), Western Blotting (WB)
43
27
13
11
8
4
2
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Showcase your results, aid the scientific community, and receive a full refund.

Contribute a validation

Learn more

Available images

Immunogen GAS2 (NP_005247, 1 a.a. ~ 111 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 4E11
Isotype IgG2a kappa
Specificity GAS2 (NP_005247, 1 a.a. ~ 111 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name GAS2 (GAS2 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 34945 DA
Gene ID 12406
NCBI Accession NP_005247
Research Area Apoptosis/Necrosis, Cell Structure
Pathways Caspase Cascade in Apoptosis
Application Notes Western blot = 1:500-1000
Comment

Background: The protein encoded by this gene is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis. It can also modulate cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-GAS2 antibody (Growth Arrest-Specific 2) (AA 1-111) (ABIN393205) Immunofluorescence of monoclonal antibody to GAS2 on NIH/3T3 cell (antibody concentra...
Immunohistochemistry (IHC) image for anti-GAS2 antibody (Growth Arrest-Specific 2) (AA 1-111) (ABIN393205) anti-Growth Arrest-Specific 2 (GAS2) (AA 1-111) antibody (Image 2)
Background publications Shimada, Miyagawa, Kawashima et al.: "An approach based on a genome-wide association study reveals candidate loci for narcolepsy." in: Human genetics, Vol. 128, Issue 4, pp. 433-41, 2010 (PubMed).

Kimura, Wakamatsu, Suzuki et al.: "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. ..." in: Genome research, Vol. 16, Issue 1, pp. 55-65, 2006 (PubMed).

Benetti, Copetti, DellOrso et al.: "The calpain system is involved in the constitutive regulation of beta-catenin signaling functions." in: The Journal of biological chemistry, Vol. 280, Issue 23, pp. 22070-80, 2005 (PubMed).

Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).

Tsutsumi, Kamata, Vokes et al.: "The novel gene encoding a putative transmembrane protein is mutated in gnathodiaphyseal dysplasia (GDD)." in: American journal of human genetics, Vol. 74, Issue 6, pp. 1255-61, 2004 (PubMed).