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IFI6 antibody (Interferon, alpha-Inducible Protein 6) (AA 1-131)

Details for Product anti-IFI6 Antibody No. ABIN393218, Supplier: Log in to see
Antigen
  • 6-16
  • FAM14C
  • G1P3
  • IFI-6-16
  • Ifi-6-16
  • IFI616
Epitope
AA 1-131
16
16
2
2
1
1
Reactivity
Human
47
2
Host
Mouse
44
3
Clonality (Clone)
Monoclonal ()
Conjugate
This IFI6 antibody is un-conjugated
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
Application
ELISA
30
23
12
6
3
1
1
Supplier
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Supplier Product No.
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Immunogen G1P3 (AAH11601, 1 a.a. ~ 131 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone M2
Isotype IgG1 kappa
Specificity G1P3 (AAH11601, 1 a.a. ~ 131 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name G1P3 (IFI6 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 12927 DA
Gene ID 12406
Research Area Apoptosis/Necrosis, Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml
Comment

Background: This gene was first identified as one of the many genes induced by interferon. The encoded protein may play a critical role in the regulation of apoptosis. A minisatellite that consists of 26 repeats of a 12 nucleotide repeating element resembling the mammalian splice donor consensus sequence begins near the end of the second exon. Alternatively spliced transcript variants that encode different isoforms by using the two downstream repeat units as splice donor sites have been described.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Johnatty, Beesley, Chen, Macgregor, Duffy, Spurdle, deFazio, Gava, Webb, Rossing, Doherty, Goodman, Lurie, Thompson, Wilkens, Ness, Moysich, Chang-Claude, Wang-Gohrke, Cramer, Terry, Hankinson, Tworoger, Garcia-Closas, Yang, Lissowska, Chanock, Pharoah, S: "Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot"." in: PLoS genetics, Vol. 6, Issue 7, pp. e1001016, 2010 (PubMed).

Szegedi, Sonkoly, Nagy, Németh, Bata-Csörgo, Kemény, Dobozy, Széll: "The anti-apoptotic protein G1P3 is overexpressed in psoriasis and regulated by the non-coding RNA, PRINS." in: Experimental dermatology, Vol. 19, Issue 3, pp. 269-78, 2010 (PubMed).

Davila, Froeling, Tan, Bonnard, Boland, Snippe, Hibberd, Seielstad: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, 2010 (PubMed).

Zhao, Peng, Li, Zhang, Zhang: "Inhibition of G1P3 expression found in the differential display study on respiratory syncytial virus infection." in: Virology journal, Vol. 5, pp. 114, 2008 (PubMed).

Barbe, Lundberg, Oksvold, Stenius, Lewin, Björling, Asplund, Pontén, Brismar, Uhlén, Andersson-Svahn: "Toward a confocal subcellular atlas of the human proteome." in: Molecular & cellular proteomics : MCP, Vol. 7, Issue 3, pp. 499-508, 2008 (PubMed).