|+1 404 474 4654|
|+1 888 205 9894 (TF)|
Calcium Channel, Voltage-Dependent, gamma Subunit 3 (CACNG3) antibody
|Synonyms||Cacng2, CACNG3, DKFZp459K1027|
Alternatives ELISA, Western Blotting (WB)
|5 references available|
|Quantity||0.1mg (1 mg/ml)|
|Price||450.00 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||CACNG3 (NP_006530, 199 a.a. ~ 298 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K|
|Description||Other names: Cacng2 calcium channel, voltage-dependent, gamma subunit 3|
|Characteristics||Purified Mouse Monoclonal Antibody (Mab)|
|Specificity||CACNG3 (NP_006530, 199 a.a. ~ 298 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Molecular Weight||35549 DA|
Background: L-type calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of several gamma subunit proteins. It is an integral membrane protein that is thought to stabilize the calcium channel in an inactive (closed) state. This protein is similar to the mouse stargazin protein, mutations in which have been associated with absence seizures, also known as petit-mal or spike-wave seizures. This gene is a member of the neuronal calcium channel gamma subunit gene subfamily of the PMP-22/EMP/MP20 family. This gene is a candidate gene for a familial infantile convulsive disorder with paroxysomal choreoathetosis.
|Application Notes||ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000|
|Buffer||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles|
|Research Area||Cell Structure, Neurology|
|Restrictions||For Research Use only|
Yap, Murate, Kishigami et al.: "Adaptor protein complex-4 (AP-4) is expressed in the central nervous system neurons and interacts with glutamate receptor delta2." in: Molecular and cellular neurosciences, Vol. 24, Issue 2, pp. 283-95, 2003 (PubMed).
Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).
Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).
Everett, Chioza, Aicardi et al.: "Linkage and association analysis of CACNG3 in childhood absence epilepsy." in: European journal of human genetics : EJHG, Vol. 15, Issue 4, pp. 463-72, 2007 (PubMed).
Correia, Bassani, Brown et al.: "Motor protein-dependent transport of AMPA receptors into spines during long-term potentiation." in: Nature neuroscience, Vol. 11, Issue 4, pp. 457-66, 2008 (PubMed).
|Reactivities||Human (23), Mouse (Murine) (21), Dog (Canine) (19), Rat (Rattus) (19), Horse (Equine) (18), Rabbit (18), Sheep (Ovine) (18), Cat (Feline) (1), Chicken (1), Cow (Bovine) (1)|
|Applications||Immunofluorescence (IF) (16), Western Blotting (WB) (12), ELISA (5), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunohistochemistry (IHC) (3), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Fixed) (IHC (fx)) (1), Immunoprecipitation (IP) (1)|
|Conjugates||Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE-Cy3 (1), PE-Cy5 (1), PE-Cy5.5 (1), PE-Cy7 (1), Un-conjugated (1)|
|Epitopes||N-Term (3), C-Term (2)|