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Distal-Less Homeobox Protein 2 (AA 1-110) antibody

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Synonyms TES-1, TES1, AW121999, Dlx-2, Tes-1, Dlx5, X-dll2, dll4, tes-1, tes1
AA 1-110
(16), (15), (10), (6), (3), (2), (2), (2), (2), (2), (1), (1), (1)
(69), (18), (7), (3), (1)
(36), (35)
Clonality (Clone)
Monoclonal ()
(2), (2), (2), (2), (2), (2), (1)
Western Blotting (WB)
(68), (53), (26), (25), (5), (2), (1), (1), (1)
Pubmed 5 references available
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Quantity 0.1 mg
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Immunogen DLX2 (NP_004396, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 2E12
Isotype IgG2a kappa
Specificity DLX2 (NP_004396, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name DLX2
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 34243 DA
Gene ID 12406
NCBI Accession NP_004396
Research Area Neurology, Cell Structure
Application Notes Western blot = 1:500-1000

Background: Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. This gene is located in a tail-to-tail configuration with another member of the gene family on the long arm of chromosome 2.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Distal-Less Homeobox Protein 2 (AA 1-110) antibody (ABIN393233) DLX2 monoclonal antibody (M05), clone 2E12 Western Blot analysis of DLX2 expression i...
Immunohistochemistry (IHC) image for anti-Distal-Less Homeobox Protein 2 (AA 1-110) antibody (ABIN393233) anti-Distal-Less Homeobox Protein 2 (AA 1-110) antibody (Image 2)
Background publications Jugessur, Shi, Gjessing et al.: "Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia." in: PLoS ONE, Vol. 5, Issue 7, pp. e11493, 2010 (PubMed).

Yerges, Klei, Cauley et al.: "High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 24, Issue 12, pp. 2039-49, 2009 (PubMed).

Laroche, Ramoz, Leroy et al.: "Polymorphisms of coding trinucleotide repeats of homeogenes in neurodevelopmental psychiatric disorders." in: Psychiatric genetics, Vol. 18, Issue 6, pp. 295-301, 2008 (PubMed).

Liu, Novosedlik, Wang et al.: "The DLX1and DLX2 genes and susceptibility to autism spectrum disorders." in: European journal of human genetics : EJHG, Vol. 17, Issue 2, pp. 228-35, 2009 (PubMed).

Espinoza, Ganga, Vadlamudi et al.: "Protein kinase C phosphorylation modulates N- and C-terminal regulatory activities of the PITX2 homeodomain protein." in: Biochemistry, Vol. 44, Issue 10, pp. 3942-54, 2005 (PubMed).

Catalog No. ABIN393233
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