Apelin (APLN) (AA 1-122) antibody

Details for Product No. ABIN393240
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms APLN, Xapelin, xnpep2, preproapelin, 6030430G11Rik, Apel, APEL, XNPEP2
Epitope
AA 1-122
(9), (6), (3), (2), (1), (1)
Reactivity
Human
(54), (19), (18)
Host
Mouse
(52), (7)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(40), (33), (17), (10), (9), (8), (7), (2), (2)
Pubmed 5 references available
Quantity 0.1 mg
Options
Shipping to United States (Change)
Availability Available
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN393240
450.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen APLN (AAH21104.1, 1 a.a. ~ 122 a.a.) full-length recombinant protein with GST tag MW of the GST tag alone is 26 K
Clone 1A8-2A5
Isotype IgG IgA IgM Mix lambda
Specificity APLN (AAH21104.1, 1 a.a. ~ 122 a.a.) full-length recombinant protein with GST tag MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name APLN
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight NONE?! DA
Gene ID 12406
Research Area Neurology, Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000
Comment

Background: This gene encodes a peptide that functions as an endogenous ligand for the G protein coupled receptor APJ. The encoded protein is synthesized as a prepropeptide that is processed into biologically active C-terminal fragments. The peptide fragments activate different tissue specific signaling pathways that regulate diverse biological functions including fluid homeostasis, cardiovascular function and insulin secretion. This protein also functions as a coreceptor for the human immunodeficiency virus 1.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
anti-Apelin (APLN) (AA 1-122) antibody Detection limit for recombinant GST tagged APLN is approximately 0.03 ng/mL as a capture antibody.
Background publications Ziora, Oświecimska, Swietochowska et al.: "Assessment of serum apelin levels in girls with anorexia nervosa." in: The Journal of clinical endocrinology and metabolism, Vol. 95, Issue 6, pp. 2935-41, 2010 (PubMed).

Niu, Wu, Zhang et al.: "Validation of genetic association in apelin-AGTRL1 system with hypertension in a larger Han Chinese population." in: Journal of hypertension, Vol. 28, Issue 9, pp. 1854-61, 2010 (PubMed).

Sonmez, Celebi, Erdem et al.: "Plasma apelin and ADMA Levels in patients with essential hypertension." in: Clinical and experimental hypertension (New York, N.Y. : 1993), Vol. 32, Issue 3, pp. 179-83, 2010 (PubMed).

Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Meral, Tascilar, Karademir et al.: "Elevated plasma levels of apelin in children with type 1 diabetes mellitus." in: Journal of pediatric endocrinology & metabolism : JPEM, Vol. 23, Issue 5, pp. 497-502, 2010 (PubMed).

Validation Images
Did you look for something else?
back to top