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Unc-5 Homolog B (C. Elegans) (UNC5B) antibody

Details for Product No. ABIN393241
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Antigen
Synonyms Unc5h2, A630020F16, D10Bwg0792e, 6330415E02Rik, UNC5H2, p53RDL1, p53rdl1, unc5h2, UNC5B, UNC5C
Reactivity
Human
(32), (17), (17), (17), (17)
Host
Mouse
(25), (5), (3)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(17), (15), (14), (13), (6), (3), (1), (1), (1)
Pubmed 5 references available
Quantity 0.1 mg
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Catalog No. ABIN393241
450.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen UNC5B (NP_734465, 27 a.a. ~ 127 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 1A9
Isotype IgG1 kappa
Specificity UNC5B (NP_734465, 27 a.a. ~ 127 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name UNC5B
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 103638 DA
Gene ID 12406
UniProt NP_734465
Research Area Neurology, Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000
Comment

Background: UNC5B belongs to a family of netrin-1 (MIM 601614) receptors thought to mediate the chemorepulsive effect of netrin-1 on specific axons. For more information on UNC5 proteins, see UNC5C (MIM 603610).

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
anti-Unc-5 Homolog B (C. Elegans) (UNC5B) antibody Detection limit for recombinant GST tagged UNC5B is approximately 1 ng/mL as a capture antibody.
Background publications Lesch, Timmesfeld, Renner et al.: "Molecular genetics of adult ADHD: converging evidence from genome-wide association and extended pedigree linkage studies." in: Journal of neural transmission (Vienna, Austria : 1996), Vol. 115, Issue 11, pp. 1573-85, 2008 (PubMed).

Hata, Kaibuchi, Inagaki et al.: "Unc5B associates with LARG to mediate the action of repulsive guidance molecule." in: The Journal of cell biology, Vol. 184, Issue 5, pp. 737-50, 2009 (PubMed).

Schubert, Denk, Mägdefrau et al.: "Role of the netrin system of repellent factors on synovial fibroblasts in rheumatoid arthritis and osteoarthritis." in: International journal of immunopathology and pharmacology, Vol. 22, Issue 3, pp. 715-22, 2009 (PubMed).

Dakouane-Giudicelli, Duboucher, Fortemps et al.: "Characterization and expression of netrin-1 and its receptors UNC5B and DCC in human placenta." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 58, Issue 1, pp. 73-82, 2009 (PubMed).

Rose, Behm, Drgon et al.: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN393241
450.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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