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Potassium Voltage-Gated Channel, Subfamily F, Member 1 (KCNF1) (AA 1-495) antibody

Details for Product No. ABIN393244, Supplier: Log in to see
Antigen
  • kcnf1
  • si:dkey-65b13.5
  • KCNF1
  • ik8
  • kh1
  • kcnf
  • kv5.1
  • IK8
  • KCNF
  • KV5.1
  • kH1
  • Gm1182
  • Kv5.1
  • Kh1
Epitope
AA 1-495
17
16
11
4
3
2
1
Reactivity
Human
47
22
18
Host
Mouse
42
5
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
31
27
11
4
3
Supplier
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Immunogen KCNF1 (AAH26110, 1 a.a. ~ 495 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 1B2-7B6
Isotype IgG2a kappa
Specificity KCNF1 (AAH26110, 1 a.a. ~ 495 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name KCNF1 (KCNF1 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 55584 DA
Gene ID 12406
Research Area Neurology, Cell Structure
Pathways
Application Notes Western blot = 1:500-1000
Comment

Background: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily F. This gene is intronless and expressed in all tissues tested, including the heart, skeletal muscle, brain, kidney, and pancreas.

Restrictions For Research Use only
Concentration 1 mg/ml
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Potassium Voltage-Gated Channel, Subfamily F, Member 1 (KCNF1) (AA 1-495) antibody (ABIN393244) KCNF1 monoclonal antibody (M01), clone 1B2-7B6 Western Blot analysis of KCNF1 express...
Background publications Cirulli, Kasperaviciūte, Attix et al.: "Common genetic variation and performance on standardized cognitive tests." in: European journal of human genetics : EJHG, Vol. 18, Issue 7, pp. 815-20, 2010 (PubMed).

Gutman, Chandy, Grissmer et al.: "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels." in: Pharmacological reviews, Vol. 57, Issue 4, pp. 473-508, 2005 (PubMed).

Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).

Strausberg, Feingold, Grouse et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, 2002 (PubMed).

Ottschytsch, Raes, Van Hoorick et al.: "Obligatory heterotetramerization of three previously uncharacterized Kv channel alpha-subunits identified in the human genome." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 12, pp. 7986-91, 2002 (PubMed).

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