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IL1RAPL1 antibody (Interleukin 1 Receptor Accessory Protein-Like 1) (AA 151-251)

Details for Product anti-IL1RAPL1 Antibody No. ABIN393248, Supplier: Log in to see
Antigen
  • 6330532G10Rik
  • C030039N24
  • IL1R8
  • IL1RAPL
  • Il1rapl
  • MRX10
  • MRX21
  • MRX34
  • OPHN4
  • TIGIRR-2
Epitope
AA 151-251
2
2
2
2
1
1
1
Reactivity
Human
58
8
8
Host
Mouse
47
11
Clonality (Clone)
Monoclonal ()
Conjugate
This IL1RAPL1 antibody is un-conjugated
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Application
ELISA, Western Blotting (WB)
55
51
39
5
4
4
1
1
Supplier
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Immunogen IL1RAPL1 (NP_055086, 151 a.a. ~ 251 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 1C10
Isotype IgG2a kappa
Specificity IL1RAPL1 (NP_055086, 151 a.a. ~ 251 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name IL1RAPL1 (IL1RAPL1 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 79969 DA
Gene ID 12406
NCBI Accession NP_055086
Research Area Neurology, Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000
Comment

Background: The protein encoded by this gene is a member of the interleukin 1 receptor family and is similar to the interleukin 1 accessory proteins. It is most closely related to interleukin 1 receptor accessory protein-like 2 (IL1RAPL2). This gene and IL1RAPL2 are located at a region on chromosome X that is associated with X-linked non-syndromic mental retardation. Deletions and mutations in this gene were found in patients with mental retardation. This gene is expressed at a high level in post-natal brain structures involved in the hippocampal memory system, which suggests a specialized role in the physiological processes underlying memory and learning abilities.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
ELISA image for anti-IL1RAPL1 antibody (Interleukin 1 Receptor Accessory Protein-Like 1) (AA 151-251) (ABIN393248) Detection limit for recombinant GST tagged IL1RAPL1 is approximately 0.3 ng/mL as a c...
Background publications Piton, Gauthier, Hamdan, Lafrenière, Yang, Henrion, Laurent, Noreau, Thibodeau, Karemera, Spiegelman, Kuku, Duguay, Destroismaisons, Jolivet, C�té, Lachapelle, Diallo, Raymond, Marineau, Champagne, Xiong, Gaspar, Rivière, Tarabeux, Cossette, Krebs, Rapopo: "Systematic resequencing of X-chromosome synaptic genes in autism spectrum disorder and schizophrenia." in: Molecular psychiatry, Vol. 16, Issue 8, pp. 867-80, 2011 (PubMed).

Romero, Friel, Velez Edwards, Kusanovic, Hassan, Mazaki-Tovi, Vaisbuch, Kim, Erez, Chaiworapongsa, Pearce, Bartlett, Salisbury, Anant, Vovis, Lee, Gomez, Behnke, Oyarzun, Tromp, Williams, Menon: "A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM)." in: American journal of obstetrics and gynecology, Vol. 203, Issue 4, pp. 361.e1-361.e30, 2010 (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Romero, Velez Edwards, Kusanovic, Hassan, Mazaki-Tovi, Vaisbuch, Kim, Chaiworapongsa, Pearce, Friel, Bartlett, Anant, Salisbury, Vovis, Lee, Gomez, Behnke, Oyarzun, Tromp, Williams, Menon: "Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes." in: American journal of obstetrics and gynecology, Vol. 202, Issue 5, pp. 431.e1-34, 2010 (PubMed).

Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, 2009 (PubMed).