|+1 404 474 4654|
|+1 888 205 9894 (TF)|
Interleukin 1 Receptor Accessory Protein-Like 1 (IL1RAPL1) antibody
|Synonyms||Il1rapl, IL1R8, MRX34, OPHN4, IL1RAPL, TIGIRR-2, C030039N24, 6330532G10Rik|
Alternatives ELISA, Western Blotting (WB)
|5 references available|
|Price||450.00 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||IL1RAPL1 (NP_055086, 151 a.a. ~ 251 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K|
|Description||Other names: IL1R8, IL1RAPL, MRX34, OPHN4, TIGIRR2 interleukin 1 receptor accessory protein-like 1|
|Characteristics||Purified Mouse Monoclonal Antibody (Mab)|
|Specificity||IL1RAPL1 (NP_055086, 151 a.a. ~ 251 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Molecular Weight||79969 DA|
Background: The protein encoded by this gene is a member of the interleukin 1 receptor family and is similar to the interleukin 1 accessory proteins. It is most closely related to interleukin 1 receptor accessory protein-like 2 (IL1RAPL2). This gene and IL1RAPL2 are located at a region on chromosome X that is associated with X-linked non-syndromic mental retardation. Deletions and mutations in this gene were found in patients with mental retardation. This gene is expressed at a high level in post-natal brain structures involved in the hippocampal memory system, which suggests a specialized role in the physiological processes underlying memory and learning abilities.
|Application Notes||ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000|
|Buffer||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles|
|Research Area||Neurology, Cell Structure|
|Restrictions||For Research Use only|
|Detection limit for recombinant GST tagged IL1RAPL1 is approximately 0.3ng/ml as a capture antibody.|
Talmud, Drenos, Shah et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, 2009 (PubMed).
Romero, Velez Edwards, Kusanovic et al.: "Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes." in: American journal of obstetrics and gynecology, Vol. 202, Issue 5, pp. 431.e1-34, 2010 (PubMed).
Piton, Gauthier, Hamdan et al.: "Systematic resequencing of X-chromosome synaptic genes in autism spectrum disorder and schizophrenia." in: Molecular psychiatry, Vol. 16, Issue 8, pp. 867-80, 2011 (PubMed).
Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).
Romero, Friel, Velez Edwards et al.: "A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM)." in: American journal of obstetrics and gynecology, Vol. 203, Issue 4, pp. 361.e1-361.e30, 2010 (PubMed).
|Reactivities||Human (22), Mouse (Murine) (21), Rat (Rattus) (21), Chicken (19), Cow (Bovine) (19), Dog (Canine) (19), Guinea Pig (18), Horse (Equine) (18), Pig (Porcine) (18), Cat (Feline) (1)|
|Applications||Immunofluorescence (IF) (17), ELISA (7), Western Blotting (WB) (5), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3), Immunoprecipitation (IP) (2), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (IHC) (1)|
|Conjugates||Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)|