TNF Receptor Associated Factor 4 (TRAF4) antibody

Antigen: TNF Receptor Associated Factor 4 (TRAF4)

Clonality: Monoclonal (2A10)

Host: Mouse

Reactivity: Human

Application: ELISA, Western Blotting (WB)

Certificates: ISO 9001:2008

Catalog no.: ABIN393274

Additional Information

Alternative name: CART1

Gene ID: 8092

UniProt: NP_008913

Immunogen: CART1 (NP_008913, 198 a.a. ~ 307 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K

Isotype: IgG2a kappa

Clone: 2A10

Description: Other names: - cartilage paired-class homeoprotein 1

Characteristics: Purified Mouse Monoclonal Antibody (Mab)

Specificity: CART1 (NP_008913, 198 a.a. ~ 307 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Molecular Weight: 36961 DA

Comments:

Background: The specific function of this gene has yet to be determined in humans, however, in rodents, it is necessary for survival of the forebrain mesenchyme and may also be involved in development of the cervix. Mutations in the mouse gene lead to neural tube defects such as acrania and meroanencephaly.

Application Details

Application Notes: ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000

Purification: Purified

Buffer: Clear, colorless solution in phosphate buffered saline, pH 7.2 .

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Neurology, Cell Structure

Restrictions: For Research Use only

Images

CART1 monoclonal antibody (M02), clone 2A10. Western Blot analysis of CART1 expression in Hela NE ( Cat # L013V3 ).

Publications

Product: Iioka, Furukawa, Yamaguchi et al.: "P300/CBP acts as a coactivator to cartilage homeoprotein-1 (Cart1), paired-like homeoprotein, through acetylation of the conserved lysine residue adjacent to the homeodomain." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 18, Issue 8, pp. 1419-29, 2003 (PubMed).

Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).

Rual, Venkatesan, Hao et al.: "Towards a proteome-scale map of the human protein-protein interaction network." in: Nature, Vol. 437, Issue 7062, pp. 1173-8, 2005 (PubMed).

Barbe, Lundberg, Oksvold et al.: "Toward a confocal subcellular atlas of the human proteome." in: Molecular & cellular proteomics : MCP, Vol. 7, Issue 3, pp. 499-508, 2008 (PubMed).

Uz, Alanay, Aktas et al.: "Disruption of ALX1 causes extreme microphthalmia and severe facial clefting: expanding the spectrum of autosomal-recessive ALX-related frontonasal dysplasia." in: American journal of human genetics, Vol. 86, Issue 5, pp. 789-96, 2010 (PubMed).