Protocadherin 1 (PCDH1) (AA 62-170) antibody

Details for Product No. ABIN393278
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Antigen
Synonyms PC42, PCDH42, 2010005A06Rik, AI585920, PCDH-1, axpc, protocadherin-1
Epitope
AA 62-170
(12), (8), (7), (6), (2), (2), (1), (1), (1), (1)
Reactivity
Human
(53), (21), (21), (18), (18), (17), (1), (1)
Host
Mouse
(39), (14)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(39), (23), (16), (15), (15), (10), (8), (8), (2), (1), (1)
Pubmed 5 references available
Quantity 0.1 mg
Options
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Catalog No. ABIN393278
450.00 $
Plus shipping costs $45.00

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Immunogen PCDH1 (NP_002578, 62 a.a. ~ 170 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 2A11
Isotype IgG2b kappa
Specificity PCDH1 (NP_002578, 62 a.a. ~ 170 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name PCDH1
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 111270 DA
Gene ID 12406
NCBI Accession NP_002578
Research Area Cell Structure, Neurology
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000
Comment

Background: This gene belongs to the protocadherin subfamily within the cadherin superfamily. The encoded protein is a membrane protein found at cell-cell boundaries. It is involved in neural cell adhesion, suggesting a possible role in neuronal development. The protein includes an extracelllular region, containing 7 cadherin-like domains, a transmembrane region and a C-terminal cytoplasmic region. Cells expressing the protein showed cell aggregation activity. Alternative splicing occurs in this gene.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Colland, Jacq, Trouplin et al.: "Functional proteomics mapping of a human signaling pathway." in: Genome research, Vol. 14, Issue 7, pp. 1324-32, 2004 (PubMed).

Ballif, Villén, Beausoleil et al.: "Phosphoproteomic analysis of the developing mouse brain." in: Molecular & cellular proteomics : MCP, Vol. 3, Issue 11, pp. 1093-101, 2004 (PubMed).

Rush, Moritz, Lee et al.: "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells." in: Nature biotechnology, Vol. 23, Issue 1, pp. 94-101, 2005 (PubMed).

Otsuki, Ota, Nishikawa et al.: "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 12, Issue 2, pp. 117-26, 2005 (PubMed).

Koppelman, Meyers, Howard et al.: "Identification of PCDH1 as a novel susceptibility gene for bronchial hyperresponsiveness." in: American journal of respiratory and critical care medicine, Vol. 180, Issue 10, pp. 929-35, 2009 (PubMed).

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