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Details for Product No. ABIN393279

Apelin (APLN) antibody

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Synonyms Apel, 6030430G11Rik, APEL, XNPEP2, APLN, Xapelin, xnpep2, preproapelin
»Alternatives Human
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
»Alternatives Un-conjugated
»Alternatives ELISA, Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN393279
Quantity 0.1 mg
450.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen APLN (AAH21104.1, 1 a.a. ~ 122 a.a.) full-length recombinant protein with GST tag MW of the GST tag alone is 26 K
Clone 2A1-2D5
Isotype IgG1 kappa
Specificity APLN (AAH21104.1, 1 a.a. ~ 122 a.a.) full-length recombinant protein with GST tag MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name APLN
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight NONE?! DA
Gene ID 12406
Research Area Neurology, Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000

Background: This gene encodes a peptide that functions as an endogenous ligand for the G protein coupled receptor APJ. The encoded protein is synthesized as a prepropeptide that is processed into biologically active C-terminal fragments. The peptide fragments activate different tissue specific signaling pathways that regulate diverse biological functions including fluid homeostasis, cardiovascular function and insulin secretion. This protein also functions as a coreceptor for the human immunodeficiency virus 1.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Ziora, Oświecimska, Swietochowska et al.: "Assessment of serum apelin levels in girls with anorexia nervosa." in: The Journal of clinical endocrinology and metabolism, Vol. 95, Issue 6, pp. 2935-41, 2010 (PubMed).

Niu, Wu, Zhang et al.: "Validation of genetic association in apelin-AGTRL1 system with hypertension in a larger Han Chinese population." in: Journal of hypertension, Vol. 28, Issue 9, pp. 1854-61, 2010 (PubMed).

Sonmez, Celebi, Erdem et al.: "Plasma apelin and ADMA Levels in patients with essential hypertension." in: Clinical and experimental hypertension (New York, N.Y. : 1993), Vol. 32, Issue 3, pp. 179-83, 2010 (PubMed).

Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Meral, Tascilar, Karademir et al.: "Elevated plasma levels of apelin in children with type 1 diabetes mellitus." in: Journal of pediatric endocrinology & metabolism : JPEM, Vol. 23, Issue 5, pp. 497-502, 2010 (PubMed).

Alternatives for antigen "Apelin (APLN)", type "Antibodies"
Hosts (45), (7)
Reactivities (46), (20), (16), (1)
Applications (35), (33), (17), (10), (7), (6), (4), (2), (2), (2)
Conjugates (5), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (10), (5), (2), (2), (1), (1)