|+1 404 474 4654|
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Glutamate-Ammonia Ligase (GLUL) antibody
|Synonyms||glul, MGC64262, GS, GLNS, PIG43, PIG59, Glns, GLUL, MGC128403, xgs, F15E12.14, F15E12_14, GLUTAMINE SYNTHETASE|
Alternatives ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
|5 references available|
|Quantity||200 uL mg|
|Price||450.00 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||GLUL (AAH10037, 1 a.a. ~ 374 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 K|
|Description||Other names: GLNS, GS glutamate-ammonia ligase (glutamine synthetase)|
|Characteristics||Purified Mouse Monoclonal Antibody (Mab)|
|Specificity||GLUL (AAH10037, 1 a.a. ~ 374 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Molecular Weight||42064 DA|
Background: The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia. Glutamine is a main source of energy and is involved in cell proliferation, inhibition of apoptosis, and cell signaling. This gene is expressed during early fetal stages, and plays an important role in controlling body pH by removing ammonia from circulation. Mutations in this gene are associated with congenital glutamine deficiency. Several alternatively spliced transcript variants have been found for this gene.
|Application Notes||ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000 Immunohistochemistry ~~ 1.5ug/ml|
|Buffer||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.Preca|
|Research Area||Cell Signaling, Cell Cycle, Neurology, Cell Structure|
|Restrictions||For Research Use only|
Di Tommaso, Destro, Seok et al.: "The application of markers (HSP70 GPC3 and GS) in liver biopsies is useful for detection of hepatocellular carcinoma." in: Journal of hepatology, Vol. 50, Issue 4, pp. 746-54, 2009 (PubMed).
Xin, Rual, Hirozane-Kishikawa et al.: "Shifted Transversal Design smart-pooling for high coverage interactome mapping." in: Genome research, Vol. 19, Issue 7, pp. 1262-9, 2009 (PubMed).
Jozwik, Pietrzycki, Jozwik et al.: "Expression of enzymes regulating placental ammonia homeostasis in human fetal growth restricted pregnancies." in: Placenta, Vol. 30, Issue 7, pp. 607-12, 2009 (PubMed).
Dal Bello, Rosa, Campanini et al.: "Glutamine synthetase immunostaining correlates with pathologic features of hepatocellular carcinoma and better survival after radiofrequency thermal ablation." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 16, Issue 7, pp. 2157-66, 2010 (PubMed).
Martins-de-Souza, Maccarrone, Wobrock et al.: "Proteome analysis of the thalamus and cerebrospinal fluid reveals glycolysis dysfunction and potential biomarkers candidates for schizophrenia." in: Journal of psychiatric research, Vol. 44, Issue 16, pp. 1176-89, 2010 (PubMed).