Glutamate-Ammonia Ligase (GLUL) antibody

Details for Product No. ABIN393284
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Antigen
Synonyms p42, GS, glns, glul, pig43, pig59, xgs, Glns, GLNS, PIG43, PIG59, MGC64262, ATGSR2, F15E12.14, F15E12_14, GLUTAMINE SYNTHETASE, glutamine synthase clone F11
Reactivity
Human
(40), (21), (19), (4), (3), (2), (1), (1), (1), (1), (1)
Host
Mouse
(38), (16), (3)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(6), (2)
Application
Western Blotting (WB)
(50), (33), (18), (17), (9), (8), (7), (3), (1)
Pubmed 5 references available
Catalog no. ABIN393284
Quantity 200 µL
Price
450.00 $   Plus shipping costs $45.00
Options
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  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen GLUL (AAH10037, 1 a.a. ~ 374 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 2B12
Isotype IgG2a kappa
Specificity GLUL (AAH10037, 1 a.a. ~ 374 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Purified
Alternative Name GLUL
Background The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia. Glutamine is a main source of energy and is involved in cell proliferation, inhibition of apoptosis, and cell signaling. This gene is expressed during early fetal stages, and plays an important role in controlling body pH by removing ammonia from circulation. Mutations in this gene are associated with congenital glutamine deficiency. Several alternatively spliced transcript variants have been found for this gene.
Synonyms: GLNS, GS glutamate-ammonia ligase (glutamine synthetase)
Molecular Weight 42064 DA
Gene ID 2752
Research Area Cell Signaling, Cell Cycle, Neurology, Cell Structure
Application Notes Western blot = 1:500-1000
Comment

Background: The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia. Glutamine is a main source of energy and is involved in cell proliferation, inhibition of apoptosis, and cell signaling. This gene is expressed during early fetal stages, and plays an important role in controlling body pH by removing ammonia from circulation. Mutations in this gene are associated with congenital glutamine deficiency. Several alternatively spliced transcript variants have been found for this gene.

Restrictions For Research Use only
Format Liquid
Buffer Phosphate buffered saline, pH 7.2
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.Preca
Expiry Date 6 months
Supplier Images
anti-Glutamate-Ammonia Ligase (GLUL) antibody GLUL monoclonal antibody (M01), clone 2B12 Western Blot analysis of GLUL expression in HeLa on formalin-fixed paraffin-embedded human tonsil (antibody concentration 0.5 µg/mL).
anti-Glutamate-Ammonia Ligase (GLUL) antibody (2) anti-Glutamate-Ammonia Ligase (GLUL) antibody (Image 2)
Background publications Di Tommaso, Destro, Seok et al.: "The application of markers (HSP70 GPC3 and GS) in liver biopsies is useful for detection of hepatocellular carcinoma." in: Journal of hepatology, Vol. 50, Issue 4, pp. 746-54, 2009 (PubMed).

Xin, Rual, Hirozane-Kishikawa et al.: "Shifted Transversal Design smart-pooling for high coverage interactome mapping." in: Genome research, Vol. 19, Issue 7, pp. 1262-9, 2009 (PubMed).

Jozwik, Pietrzycki, Jozwik et al.: "Expression of enzymes regulating placental ammonia homeostasis in human fetal growth restricted pregnancies." in: Placenta, Vol. 30, Issue 7, pp. 607-12, 2009 (PubMed).

Dal Bello, Rosa, Campanini et al.: "Glutamine synthetase immunostaining correlates with pathologic features of hepatocellular carcinoma and better survival after radiofrequency thermal ablation." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 16, Issue 7, pp. 2157-66, 2010 (PubMed).

Martins-de-Souza, Maccarrone, Wobrock et al.: "Proteome analysis of the thalamus and cerebrospinal fluid reveals glycolysis dysfunction and potential biomarkers candidates for schizophrenia." in: Journal of psychiatric research, Vol. 44, Issue 16, pp. 1176-89, 2010 (PubMed).

Hosts (38), (16), (3)
Reactivities (40), (21), (19), (4), (3), (2), (1), (1), (1), (1), (1)
Applications (50), (33), (18), (17), (9), (8), (7), (3), (1)
Conjugates (6), (2)
Epitopes (6), (6), (6), (2), (1), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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