You are viewing an incomplete version of our website. Please click to reload the website as full version.

Visinin-Like 1 (VSNL1) (AA 1-192) antibody

Details for Product No. ABIN393301, Supplier: Log in to see
Antigen
  • HLP3
  • hlp3
  • hpcal3
  • HPCAL3
  • HUVISL1
  • huvisl1
  • MGC132057
  • MGC146004
  • Nvp1
  • Ratnvp1
  • si:dkey-15f12.11
  • si:dkey-30j22.11
  • VILIP
  • vilip
  • vilip-1
  • VILIP-1
  • Vnsl1
  • VSNL1
  • zgc:103644
Epitope
AA 1-192
75
20
18
14
10
9
5
3
3
2
2
1
Reactivity
Human
248
77
65
55
1
Host
Mouse
164
73
7
4
1
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
7
6
6
6
4
4
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Application
Western Blotting (WB)
229
63
59
54
46
31
17
4
2
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Immunogen VSNL1 (AAH22012, 1 a.a. ~ 192 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 2F1-E3
Isotype IgG2a kappa
Specificity VSNL1 (AAH22012, 1 a.a. ~ 192 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name VSNL1 (VSNL1 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 22142 DA
Gene ID 12406
Research Area Cell Signaling, Cell Structure, Neurology
Application Notes Western blot = 1:500-1000
Comment

Background: This gene is a member of the visinin/recoverin subfamily of neuronal calcium sensor proteins. The encoded protein is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium-dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Visinin-Like 1 (VSNL1) (AA 1-192) antibody (ABIN393301) Western Blot analysis of VSNL1 expression in transfected 293T cell line by VSNL1 mono...
Immunohistochemistry (IHC) image for anti-Visinin-Like 1 (VSNL1) (AA 1-192) antibody (ABIN393301) anti-Visinin-Like 1 (VSNL1) (AA 1-192) antibody (Image 2)
Background publications Xu, Li, Zhang, Zhang, Zhang, Huang, Sun, Ren, Sui, Liu: "MicroRNAs and target site screening reveals a pre-microRNA-30e variant associated with schizophrenia." in: Schizophrenia research, Vol. 119, Issue 1-3, pp. 219-27, 2010 (PubMed).

Buttgereit, Qadri, Monti, Langenickel, Dietz, Braunewell, Bader: "Visinin-like protein 1 regulates natriuretic peptide receptor B in the heart." in: Regulatory peptides, Vol. 161, Issue 1-3, pp. 51-7, 2010 (PubMed).

Fu, Zhang, Jin, Patchefsky, Braunewell, Klein-Szanto: "Promoter regulation of the visinin-like subfamily of neuronal calcium sensor proteins by nuclear respiratory factor-1." in: The Journal of biological chemistry, Vol. 284, Issue 40, pp. 27577-86, 2009 (PubMed).

Chen, Wang, Chang: "Regulatory elements and functional implication for the formation of dimeric visinin-like protein-1." in: Journal of peptide science : an official publication of the European Peptide Society, Vol. 15, Issue 2, pp. 89-94, 2009 (PubMed).

Zhao, Noack, Brackmann, Gloveli, Maelicke, Heinemann, Anand, Braunewell: "Neuronal Ca2+ sensor VILIP-1 leads to the upregulation of functional alpha4beta2 nicotinic acetylcholine receptors in hippocampal neurons." in: Molecular and cellular neurosciences, Vol. 40, Issue 2, pp. 280-92, 2009 (PubMed).