Visinin-Like 1 (VSNL1) antibody

Details for Product No. ABIN393301
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Antigen
Synonyms HLP3, VILIP, HPCAL3, HUVISL1, VILIP-1, Nvp1, Ratnvp1, Vnsl1, MGC132057, MGC146004, VSNL1, si:dkey-15f12.11, si:dkey-30j22.11, zgc:103644, hlp3, vilip, hpcal3, huvisl1, vilip-1
Reactivity
Human
(74), (27), (21), (17), (13)
Host
Mouse
(36), (35), (2), (1), (1)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(61), (14), (13), (12), (10), (6), (5), (4), (2), (2), (2), (1)
Pubmed 5 references available
Catalog no. ABIN393301
Quantity 0.1 mg
Price
450.00 $   Plus shipping costs $45.00
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Immunogen VSNL1 (AAH22012, 1 a.a. ~ 192 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 2F1-E3
Isotype IgG2a kappa
Specificity VSNL1 (AAH22012, 1 a.a. ~ 192 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name VSNL1
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 22142 DA
Gene ID 12406
Research Area Cell Signaling, Cell Structure, Neurology
Application Notes Western blot = 1:500-1000
Comment

Background: This gene is a member of the visinin/recoverin subfamily of neuronal calcium sensor proteins. The encoded protein is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium-dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
anti-Visinin-Like 1 (VSNL1) antibody Western Blot analysis of VSNL1 expression in transfected 293T cell line by VSNL1 monoclonal antibody (M01), clone 2F1-E3. Lane 1: VSNL1 transfected lysate(22.1 KDa). Lane 2: Non-transfected lysate. Detection limit for recombinant GST tagged VSNL1 is approximately 0.3 ng/mL as a capture antibody.
anti-Visinin-Like 1 (VSNL1) antibody (2) anti-Visinin-Like 1 (VSNL1) antibody (Image 2)
Background publications Zhao, Noack, Brackmann et al.: "Neuronal Ca2+ sensor VILIP-1 leads to the upregulation of functional alpha4beta2 nicotinic acetylcholine receptors in hippocampal neurons." in: Molecular and cellular neurosciences, Vol. 40, Issue 2, pp. 280-92, 2009 (PubMed).

Chen, Wang, Chang: "Regulatory elements and functional implication for the formation of dimeric visinin-like protein-1." in: Journal of peptide science : an official publication of the European Peptide Society, Vol. 15, Issue 2, pp. 89-94, 2009 (PubMed).

Fu, Zhang, Jin et al.: "Promoter regulation of the visinin-like subfamily of neuronal calcium sensor proteins by nuclear respiratory factor-1." in: The Journal of biological chemistry, Vol. 284, Issue 40, pp. 27577-86, 2009 (PubMed).

Buttgereit, Qadri, Monti et al.: "Visinin-like protein 1 regulates natriuretic peptide receptor B in the heart." in: Regulatory peptides, Vol. 161, Issue 1-3, pp. 51-7, 2010 (PubMed).

Xu, Li, Zhang et al.: "MicroRNAs and target site screening reveals a pre-microRNA-30e variant associated with schizophrenia." in: Schizophrenia research, Vol. 119, Issue 1-3, pp. 219-27, 2010 (PubMed).

Hosts (36), (35), (2), (1), (1)
Reactivities (74), (27), (21), (17), (13)
Applications (61), (14), (13), (12), (10), (6), (5), (4), (2), (2), (2), (1)
Conjugates (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (5), (2), (2), (2), (1), (1)
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