Search, Find and Buy Antibodies, ELISA Kits and Proteins.
Loading Loading
Order hotline:
phone +1 404 474 4654
fax +1 888 205 9894 (TF)
Details for Product No. ABIN393312

Chimerin 1 (CHN1) antibody

Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Synonyms ARHGAP2, AI413815, 0610007I19Rik, 0710001E19Rik, 1700112L09Rik, 2900046J01Rik, CHN, DURS2, NC, RHOGAP2, chimaerin, wu:fr89a09, zgc:56160, zgc:92906, N-chimaerin
»Alternatives Human
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
»Alternatives Un-conjugated
»Alternatives ELISA, Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN393312
Quantity 0.1 mg
450.00 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 2 to 3 Business Days
Immunogen CHN1 (AAH11393, 91 a.a. ~ 201 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 3A3
Isotype IgG2a kappa
Specificity CHN1 (AAH11393, 91 a.a. ~ 201 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name CHN1
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 53172 DA
Gene ID 12406
Research Area Neurology, Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000

Background: This gene encodes GTPase-activating protein for p21-rac and a phorbol ester receptor. It plays an important role in ocular motor axon pathfinding. Heterozygous missense mutations in this gene cause Duane's retraction syndrome 2 (DURS2). Multiple transcript variants encoding different isoforms have been found for this gene.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Murillo-Correa, Kon-Jara, Engle et al.: "Clinical features associated with an I126M alpha2-chimaerin mutation in a family with autosomal-dominant Duane retraction syndrome." in: Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus / American Association for Pediatric Ophthalmology and Strabismus, Vol. 13, Issue 3, pp. 245-8, 2009 (PubMed).

Miyake, Andrews, Fan et al.: "CHN1 mutations are not a common cause of sporadic Duane's retraction syndrome." in: American journal of medical genetics. Part A, Vol. 152A, Issue 1, pp. 215-7, 2009 (PubMed).

Rose, Behm, Drgon et al.: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).

Dick, Meyers, Aliev et al.: "Evidence for genes on chromosome 2 contributing to alcohol dependence with conduct disorder and suicide attempts." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 153B, Issue 6, pp. 1179-88, 2010 (PubMed).

Volk, Fricke, Strobl et al.: "Analysis of the CHN1 gene in patients with various types of congenital ocular motility disorders." in: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, Vol. 248, Issue 9, pp. 1351-7, 2010 (PubMed).

Alternatives for antigen "Chimerin 1 (CHN1)", type "Antibodies"
Hosts (27), (19)
Reactivities (46), (18), (18), (13), (13), (1), (1), (1), (1), (1)
Applications (37), (11), (10), (8), (6), (3), (2), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (3), (3), (2), (2), (2), (1), (1)