You are viewing an incomplete version of our website. Please click to reload the website as full version.

ADAM11 antibody (ADAM Metallopeptidase Domain 11) (AA 230-334)

Details for Product anti-ADAM11 Antibody No. ABIN393325, Supplier: Log in to see
Antigen
  • DKFZp459F101
  • AW060611
  • Mdc
  • MDC
  • mdc
  • mdc11a
  • xMDC11
Epitope
AA 230-334
16
15
3
2
2
Reactivity
Human
37
15
15
Host
Mouse
33
4
Clonality (Clone)
Monoclonal ()
Conjugate
This ADAM11 antibody is un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
25
20
11
3
2
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Showcase your results, aid the scientific community, and receive a full refund.

Contribute a validation

Learn more

Available images

Immunogen ADAM11 (NP_002381, 230 a.a. ~ 334 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 3D4
Isotype IgG2b kappa
Specificity ADAM11 (NP_002381, 230 a.a. ~ 334 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name ADAM11 (ADAM11 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 83418 DA
Gene ID 12406
NCBI Accession NP_002381
Research Area Cell Signaling, Cell Structure, Cancer, Neurology
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000
Comment

Background: This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene represents a candidate tumor supressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
ELISA image for anti-ADAM11 antibody (ADAM Metallopeptidase Domain 11) (AA 230-334) (ABIN393325) Detection limit for recombinant GST tagged ADAM11 is approximately 0.1 ng/mL as a cap...
Background publications Stelzl, Worm, Lalowski et al.: "A human protein-protein interaction network: a resource for annotating the proteome. ..." in: Cell, Vol. 122, Issue 6, pp. 957-68, 2005 (PubMed).

Fu, Wang, Yang et al.: "Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes." in: Genomics, Vol. 84, Issue 1, pp. 205-10, 2004 (PubMed).

Brandenberger, Wei, Zhang et al.: "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation." in: Nature biotechnology, Vol. 22, Issue 6, pp. 707-16, 2004 (PubMed).

Hillman, Green, Brenner: "An unappreciated role for RNA surveillance." in: Genome biology, Vol. 5, Issue 2, pp. R8, 2004 (PubMed).

Strausberg, Feingold, Grouse et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, 2002 (PubMed).