ATPase Type 13A2 (ATP13A2) (AA 68-155) antibody

Details for Product No. ABIN393340
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Antigen
Synonyms RGD1307977, ATP13A2, im:7147302, zgc:136762, CLN12, HSA9947, KRPPD, PARK9, 1110012E06Rik, AA589443
Epitope
AA 68-155
(7), (7), (6), (5), (2), (1), (1), (1), (1)
Reactivity
Human
(36), (26), (17), (17), (17)
Host
Mouse
(37), (2)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(21), (15), (10), (10), (7), (3), (3), (1)
Pubmed 5 references available
Quantity 0.1 mg
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Catalog No. ABIN393340
450.00 $
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Immunogen ATP13A2 (NP_071372, 68 a.a. ~ 155 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 4B7
Isotype IgG2a kappa
Specificity ATP13A2 (NP_071372, 68 a.a. ~ 155 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name ATP13A2
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 128794 DA
Gene ID 12406
NCBI Accession NP_071372
Research Area Neurology, Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000
Comment

Background: This gene encodes a member of the P5 subfamily of ATPases which transports inorganic cations as well as other substrates. Mutations in this gene are associated with Kufor-Rakeb syndrome (KRS), also referred to as Parkinson disease 9. Multiple transcript variants encoding different isoforms have been found for this gene.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
anti-ATPase Type 13A2 (ATP13A2) (AA 68-155) antibody Detection limit for recombinant GST tagged ATP13A2 is approximately 0.1 ng/mL as a capture antibody.
Background publications Wang, Guo, Nie et al.: "A new variant of the ATP13A2 gene in Chinese patients with early-onset parkinsonism." in: Chinese medical journal, Vol. 122, Issue 24, pp. 3082-5, 2010 (PubMed).

Okada, Kamatani, Takahashi et al.: "A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci." in: Human molecular genetics, Vol. 19, Issue 11, pp. 2303-12, 2010 (PubMed).

Fei, Cao, Xiao et al.: "Lack of association between ATP13A2 Ala746Thr variant and Parkinson's disease in Han population of mainland China." in: Neuroscience letters, Vol. 475, Issue 2, pp. 61-3, 2010 (PubMed).

Reetz, Tadic, Kasten et al.: "Structural imaging in the presymptomatic stage of genetically determined parkinsonism." in: Neurobiology of disease, Vol. 39, Issue 3, pp. 402-8, 2010 (PubMed).

Dos Santos, Pestana, Diniz et al.: "Mutational analysis of GIGYF2, ATP13A2 and GBA genes in Brazilian patients with early-onset Parkinson's disease." in: Neuroscience letters, Vol. 485, Issue 2, pp. 121-4, 2010 (PubMed).

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