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Distal-Less Homeobox Protein 2 antibody
Alternatives ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
|5 references available|
|Price||450.00 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||DLX2 (NP_004396, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K|
|Description||Other names: TES1, TES1 distal-less homeobox 2|
|Characteristics||Purified Mouse Monoclonal Antibody (Mab)|
|Specificity||DLX2 (NP_004396, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Molecular Weight||34243 DA|
Background: Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. This gene is located in a tail-to-tail configuration with another member of the gene family on the long arm of chromosome 2.
|Application Notes||ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000 Immunohistochemistry ~~ 1.5ug/ml|
|Buffer||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles|
|Research Area||Neurology, Cell Structure|
|Restrictions||For Research Use only|
Espinoza, Ganga, Vadlamudi et al.: "Protein kinase C phosphorylation modulates N- and C-terminal regulatory activities of the PITX2 homeodomain protein." in: Biochemistry, Vol. 44, Issue 10, pp. 3942-54, 2005 (PubMed).
Liu, Novosedlik, Wang et al.: "The DLX1and DLX2 genes and susceptibility to autism spectrum disorders." in: European journal of human genetics : EJHG, Vol. 17, Issue 2, pp. 228-35, 2009 (PubMed).
Laroche, Ramoz, Leroy et al.: "Polymorphisms of coding trinucleotide repeats of homeogenes in neurodevelopmental psychiatric disorders." in: Psychiatric genetics, Vol. 18, Issue 6, pp. 295-301, 2008 (PubMed).
Yerges, Klei, Cauley et al.: "High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 24, Issue 12, pp. 2039-49, 2009 (PubMed).
Jugessur, Shi, Gjessing et al.: "Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia." in: PLoS ONE, Vol. 5, Issue 7, pp. e11493, 2010 (PubMed).
|Hosts||Rabbit (26), Mouse (10)|
|Reactivities||Human (35), Mouse (Murine) (24), Dog (Canine) (20), Cow (Bovine) (19), Rat (Rattus) (19), Chicken (18), Horse (Equine) (18), Pig (Porcine) (18), Rabbit (18)|
|Applications||Western Blotting (WB) (21), ELISA (16), Immunofluorescence (IF) (15), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (13), Immunohistochemistry (IHC) (6), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Fixed) (IHC (fx)) (1)|
|Conjugates||Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE-Cy3 (1), PE-Cy5 (1), PE-Cy5.5 (1), PE-Cy7 (1), Un-conjugated (1)|
|Epitopes||AA 24-39 (1), C-Term (1), Center (1), Internal Region (1), N-Term (1)|